Akbarieh M, Dubuc B, Tawashi R
Faculty of Pharmacy, University of Montreal, Quebec, Canada.
Scanning Microsc. 1987 Sep;1(3):1397-403.
Single crystals of Calcium Oxalate Dihydrate (COD) were grown from solution under controlled release of the reacting ions. Dissolution of COD was studied at different pH levels and in different dilutions of urine. The descriptors of the contour were determined during dissolution of COD using a quantitative morphological technique. The shape parameters and surface ruggedness were determined from Fourier and fractal analysis. The results obtained give quantitative information on the dissolution kinetics and the surface geometry of COD crystals in normal and diluted urine. Dissolution inhibition and morphological changes of COD crystals during dissolution were attributed to selective adsorption of urine non-ionic macromolecules on the crystal stepped surface. Surface etching of COD was found to depend on urine dilution and time of incubation. The data obtained suggest that the geometric structure of the surface is likely to be a potential factor in understanding crystal aggregation in stone formation.
在反应离子的可控释放条件下，从溶液中生长出二水合草酸钙（COD）单晶。研究了COD在不同pH值水平和不同尿液稀释度下的溶解情况。在COD溶解过程中，使用定量形态学技术确定轮廓的描述符。通过傅里叶分析和分形分析确定形状参数和表面粗糙度。所得结果提供了关于正常尿液和稀释尿液中COD晶体溶解动力学和表面几何形状的定量信息。COD晶体在溶解过程中的溶解抑制和形态变化归因于尿液非离子大分子在晶体阶梯表面的选择性吸附。发现COD的表面蚀刻取决于尿液稀释度和孵育时间。获得的数据表明，表面的几何结构可能是理解结石形成中晶体聚集的一个潜在因素。
