Oshima Akito, Kimura Toshikazu, Akabane Atsuya, Inoue Tomohiro
Department of Neurosurgery, NTT Medical Center Tokyo, Tokyo, Japan.
Department Neurosurgery, Yokohama City University, Graduate School of Medicine, Fukuura, Kanazawa-ku, Yokohama, Japan.
Surg Neurol Int. 2022 Dec 9;13:574. doi: 10.25259/SNI_703_2022. eCollection 2022.
The biology and clinical course of intracranial germinomas differ as per their location of occurrence. Germinoma of the primary midbrain is particularly rare, and its clinical features, treatment strategies, and long-term prognosis remain uncertain.
A 39-year-old man who had been diagnosed with midbrain germinoma by open biopsy through the occipital transtentorial approach had undergone chemoradiotherapy and achieved 5 years with no recurrence.
Germinomas should be considered as a differential diagnosis for adolescents and young adult men with mesencephalic tumors, and reliable sampling followed by chemoradiotherapy must be performed.
颅内生殖细胞瘤的生物学特性和临床病程因其发生部位而异。原发性中脑生殖细胞瘤尤为罕见，其临床特征、治疗策略及长期预后仍不明确。
一名39岁男性，通过枕下经小脑幕入路开放活检确诊为中脑生殖细胞瘤，接受了放化疗，5年无复发。
对于患有中脑肿瘤的青少年及青年男性，应将生殖细胞瘤作为鉴别诊断之一，必须进行可靠的取样，随后进行放化疗。
