Yin Jianyi, Wu Eric, Jan Jenny, Gray Toby, Shah Shawn L, Enwerem Ngozi
Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
ACG Case Rep J. 2022 Dec 26;9(12):e00937. doi: 10.14309/crj.0000000000000937. eCollection 2022 Dec.
Eosinophilic gastrointestinal diseases are rare disorders characterized by infiltration of eosinophils in one or multiple segments of the gastrointestinal tract. Hypersensitivity to food or environmental allergens is believed to play an important role in the pathogenesis. In this case report, we describe a 61-year-old man who developed eosinophilic gastroenteritis and colitis with severe peripheral eosinophilia after intragastric balloon (IGB) placement for weight loss. His symptoms and peripheral eosinophilia improved rapidly after removal of the IGB without the need for immunomodulatory therapies or diet modifications. This case suggests a possible association between IGB and eosinophilic gastrointestinal diseases, which warrants clinicians' awareness and further studies.
嗜酸性胃肠道疾病是一种罕见的疾病,其特征是胃肠道的一个或多个节段有嗜酸性粒细胞浸润。食物或环境过敏原的超敏反应被认为在发病机制中起重要作用。在本病例报告中,我们描述了一名61岁男性,他在放置胃内球囊(IGB)减肥后发生了嗜酸性胃肠炎和结肠炎,并伴有严重的外周嗜酸性粒细胞增多。在移除IGB后,他的症状和外周嗜酸性粒细胞增多迅速改善,无需免疫调节治疗或饮食调整。该病例提示IGB与嗜酸性胃肠道疾病之间可能存在关联,值得临床医生关注并进一步研究。