Barrichello Sérgio, Ribeiro Igor Braga, de Souza Thiago F, Galvão Neto Manoel Dos Passos, Grecco Eduardo, Waisberg Jaques
Department of Gastrointestinal Surgery, Faculdade de Medicina do ABC (FMABC), Santo André, BRA.
Serviço de Endoscopia Gastrointestinal do Departamento de Gastroenterologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, BRA.
Cureus. 2022 Dec 16;14(12):e32599. doi: 10.7759/cureus.32599. eCollection 2022 Dec.
Background Obesity is the most well-established and prolonged pandemic in modern society. Having a better understanding of the available tools is important to improve weight loss and make the strategies more productive. This study aims to evaluate the effect of intragastric balloon (IGB) on gastric emptying time, its relationship with weight loss after IGB removal, and weight maintenance after six years. Methodology This prospective study analyzed data from patients undergoing IGB placement. A six-years follow-up was performed and data about weight maintenance were collected. We analyzed the impact of the IGB on gastrointestinal motility and its correlation with weight loss. Results Of the 20 patients included in the study, 52.4% were diagnosed with class I obesity and 47.6% with class II obesity. The mean weight of the patients was 96.5 ± 11.9 kg at baseline, 79.6 ± 11.4 kg at the time of IGB removal, 81.8 ± 9.1 kg at six months, and 93.2 ± 14.3 kg six years after IGB removal. The mean difference between the initial weight and that measured immediately after IGB removal was 16.68 ± 5.71 kg. Regarding gastric emptying time, there was a difference in retention on comparing the measurement before balloon placement to that after the balloon was in place (72.9% vs. 86.8%) after one hour of food intake. Comparing two hours after food intake, patients before IGB placement had a 30.6% food retention, while patients with IGB in place had a 69.2% retention. Conclusions In patients with class I or II obesity, the use of an IGB delayed gastric emptying of foods but showed no direct correlation with weight loss. Weight loss achieved after IGB placement was maintained in half of the patients at a six-year follow-up.
背景 肥胖是现代社会中最广为人知且持续时间长的流行病。更好地了解现有工具对于促进体重减轻并使策略更有成效至关重要。本研究旨在评估胃内球囊（IGB）对胃排空时间的影响、其与IGB取出后体重减轻的关系以及六年之后的体重维持情况。方法 这项前瞻性研究分析了接受IGB植入患者的数据。进行了为期六年的随访并收集了有关体重维持的数据。我们分析了IGB对胃肠动力的影响及其与体重减轻的相关性。结果 纳入研究的20例患者中，52.4%被诊断为I级肥胖，47.6%为II级肥胖。患者的平均体重在基线时为96.5±11.9千克，IGB取出时为79.6±11.4千克，六个月时为81.8±9.1千克，IGB取出六年之后为93.2±14.3千克。初始体重与IGB取出后立即测量的体重之间的平均差异为16.68±5.71千克。关于胃排空时间，进食一小时后，比较球囊放置前与球囊放置后的测量结果，潴留情况存在差异（72.9%对86.8%）。进食两小时后比较，IGB放置前的患者食物潴留率为3%。结论 在I级或II级肥胖患者中，使用IGB会延迟食物的胃排空，但与体重减轻无直接相关性。在六年的随访中，IGB放置后实现的体重减轻在一半的患者中得以维持。
