Tallroth K
Department of Radiology, Orthopaedic Hospital of the Invalid Foundation, Helsinki, Finland.
Spine (Phila Pa 1976). 1987 Jul-Aug;12(6):574-6. doi: 10.1097/00007632-198707000-00013.
Twenty-seven metrizamide myelographies were performed in 26 patients who had a history of iodine allergy or adverse reactions to iodinated contrast media. Three of the patients had had adverse reactions from a previous myelography procedure. All patients received atropine, diazepam, and metoclopramide as premedication. In ten examinations corticosteroids were also given. No patient, during or after myelography, had any reaction that could be related to hypersensitivity to the contrast medium. The incidence of headache, the most frequent side effect, was almost the same in patients who had corticosteroids in their premedication (30%) as in patients without (35%). These observations indicate that metrizamide myelography may be performed despite previous adverse reactions to contrast media.
对26例有碘过敏史或对碘化造影剂有不良反应的患者进行了27次甲泛葡胺脊髓造影。其中3例患者曾在之前的脊髓造影检查中出现过不良反应。所有患者均接受阿托品、地西泮和甲氧氯普胺作为术前用药。在10次检查中还给予了皮质类固醇。在脊髓造影期间或之后，没有患者出现任何可能与造影剂过敏相关的反应。最常见的副作用头痛的发生率，在术前使用皮质类固醇的患者中（30%）与未使用的患者中（35%）几乎相同。这些观察结果表明，尽管之前对造影剂有不良反应，仍可进行甲泛葡胺脊髓造影。
