Wang Mingjia, Leong May Ying, Tan Qing Ting
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Pathology and Laboratory Medicine, Histopathology, KK Women's and Children's Hospital, Singapore, Singapore.
J Surg Case Rep. 2022 Dec 30;2022(12):rjac602. doi: 10.1093/jscr/rjac602. eCollection 2022 Dec.
Fibroadenomas are benign breast tumors with a rare incidence of malignant transformation. Carcinoma arising within fibroadenomas typically occurs in women above the age of 40. We present a case of a young patient with microinvasive carcinoma arising within a biopsy-proven fibroadenoma, highlighting the possibility of carcinoma arising within fibroadenomas in young patients and the importance of vigilant surveillance even after a benign biopsy. In younger patients, new suspicious changes in benign lesions should be investigated. If prior core needle biopsy was performed, excision biopsy should be considered as the malignancy may be small and may be missed on needle biopsy.
纤维腺瘤是一种良性乳腺肿瘤,发生恶性转化的几率很低。纤维腺瘤内发生的癌通常见于40岁以上的女性。我们报告一例年轻患者,其在经活检证实的纤维腺瘤内发生了微浸润癌,强调了年轻患者纤维腺瘤内发生癌的可能性,以及即使活检为良性后仍需警惕监测的重要性。对于年轻患者,良性病变出现新的可疑变化时应进行检查。如果之前进行过粗针活检,应考虑切除活检,因为恶性肿瘤可能很小,在针吸活检时可能会漏诊。