起源于纤维腺瘤的导管原位癌：1例罕见病例并文献复习
Ductal carcinoma in situ arising from fibroadenoma; a rare case with review of literature.
作者信息
Hammood Zuhair D, Mohammed Shvan H, Abdulla Berwn A, Omar Sami S, Naqar Sharo, Salih Abdulwahid M, Kakamad Fahmi H
机构信息
Smart Health Tower, Madam Mitterrand Street, Sulaimani, Kurdistan, Iraq.
Kscien Organization, Hamdi Str, Azadi Mall, Sulaimani, Kurdistan, Iraq.
出版信息
Ann Med Surg (Lond). 2022 Mar 2;75:103449. doi: 10.1016/j.amsu.2022.103449. eCollection 2022 Mar.
INTRODUCTION
ibroadenoma (FA) is a common benign breast mass representing a group of hyperplastic breast lobules due to the deviation of normal development. This study aims to present a rare case of ductal carcinoma in situ (DCIS) associated with fibroadenoma.
CASE REPORT
A 49-year-old married female presents with a right breast mass for five years. Core needle biopsy diagnosed the specimen as cellular complex fibroadenoma. A breast-lumpectomy and the histopathological examination of the surgical specimen confirmed ductal carcinoma in-situ.
DISCUSSION
Malignant changes within fibroadenomas typically happen at an older age, with the age of detection in the fifth decade. Complex fibroadenomas are more related to malignant transformation. Old age and strong family history are risk factors for malignant transformation of fibroadenomas.
CONCLUSION
Fibroadenomas are common benign tumors. They can rarely be associated with DCIS. Therefore, the risk of malignancy should always be kept in mind.
引言
纤维腺瘤（FA）是一种常见的乳腺良性肿块，代表一组因正常发育偏差而形成的乳腺小叶增生。本研究旨在呈现一例罕见的与纤维腺瘤相关的导管原位癌（DCIS）病例。
病例报告
一名49岁已婚女性，右乳肿块已存在五年。粗针活检将标本诊断为细胞性复杂纤维腺瘤。乳房肿块切除术及手术标本的组织病理学检查证实为导管原位癌。
讨论
纤维腺瘤内的恶性变化通常发生在年龄较大时，确诊年龄多在五十多岁。复杂纤维腺瘤与恶性转化的关系更为密切。高龄和家族病史强烈是纤维腺瘤恶性转化的危险因素。
结论
纤维腺瘤是常见的良性肿瘤。它们很少会与导管原位癌相关。因此，应始终牢记恶性风险。
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