Amiot Aurelien, Bourrier Anne, Gornet Jean-Marc, Dewit Olivier, Nancey Stephane, Altwegg Romain, Abitbol Vered, Laharie David, Reenaers Catherine, Gagnière Charlotte, Buisson Anthony, Nachury Maria, Viennot Stephanie, Vuitton Lucine, Stefanescu Carmen, Marteau Philippe, Bouguen Guillaume, Seksik Philippe
Department of Gastroenterology, Bicêtre Hospital, AP-HP, Paris Est Creteil University, Le Kremlin Bicêtre, France.
Saint Antoine Hospital, Gastroenterology Unit, Centre de Recherche Saint-Antoine, Sorbonne Université, INSERM 75012, Assistance Publique-Hôpitaux de Paris, France.
Infect Prev Pract. 2023 Mar;5(1):100267. doi: 10.1016/j.infpip.2022.100267. Epub 2022 Dec 30.
Whether healthcare workers with inflammatory bowel disease (IBD) are at increased risk of Novel coronavirus disease (COVID-19) due to occupational exposure is unknown.
To assess the risk of COVID-19 in healthcare workers with IBD.
A case control study enrolled 326 healthcare workers with IBD from 17 GETAID centres and matched non-healthcare workers with IBD controls (1:1) for gender, age, disease subtype and year of diagnosis. The study period was year 2020 during the COVID-19 outbreak.
In total, 59 COVID-19 were recorded among cases (n = 32) and controls (n = 27), including 2 severe COVID-19 (requiring hospitalization, mechanic ventilation) but no death. No difference was observed between healthcare workers and controls regarding the overall incidence rates of COVID-19 4.9 ± 2.2 . 3.8 ± 1.9 per 100 patient-semesters, = 0.34) and the overall incidence rates of severe COVID-19 (0.6 ± 7.8 . 0.3 ± 5.5 per 100 patient-semesters, = 0.42). In multivariate analysis in the entire study population, COVID-19 was associated with patients with body mass index > 30 kg/m (HR = 2.48, 95%CI [1.13-5.44], = 0.02).
Healthcare workers with IBD do not have an increased risk of COVID-19 compared with other patients with IBD.
患有炎症性肠病（IBD）的医护人员是否因职业暴露而面临新型冠状病毒病（COVID-19）风险增加尚不清楚。
评估患有IBD的医护人员感染COVID-19的风险。
一项病例对照研究纳入了来自17个GETAID中心的326名患有IBD的医护人员，并为其匹配了性别、年龄、疾病亚型和诊断年份相匹配的非医护人员IBD对照（1:1）。研究期间为2020年COVID-19疫情期间。
病例组（n = 32）和对照组（n = 27）共记录了59例COVID-19，包括2例重症COVID-19（需要住院、机械通气），但无死亡病例。医护人员和对照组在COVID-19的总体发病率（每100患者学期4.9±2.2. 3.8±1.9，P = 0.34）和重症COVID-19的总体发病率（每100患者学期0.6±7.8. 0.3±5.5，P = 0.42）方面未观察到差异。在整个研究人群的多变量分析中，COVID-19与体重指数> 30 kg/m的患者相关（HR = 2.48，95%CI [1.13 - 5.44]，P = 0.02）。
与其他患有IBD的患者相比，患有IBD的医护人员感染COVID-19的风险并未增加。
