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一款针对40岁以上高加索女性眼周区域的化妆品的功效评估

Efficacy Evaluation of a Cosmetic Product for the Periocular Area in Caucasian Women Aged Over 40 Years Old.

作者信息

Nobile Vincenzo, Spartà Eleonora, Zanoletti Valentina, Sandolo Francesco, Cestone Enza

机构信息

R&D Department, Complife Italia, San Martino Siccomario, PV, Italy.

In vivo Testing Department, Complife Italia, San Martino Siccomario, PV, Italy.

出版信息

Clin Cosmet Investig Dermatol. 2022 Dec 29;15:2933-2941. doi: 10.2147/CCID.S377930. eCollection 2022.

Abstract

PURPOSE

The present study was aimed at evaluating the efficacy of a cosmetic product in improving the appearance of periocular skin.

PATIENTS AND METHODS

An open-label study on 40 female subjects showing clinical signs of skin aging in the periocular area (including bags under the eye and dark circles) was conducted. At day 0 and day 28 the bags under eye volume, dark circles color, skin texture, skin moisturization, skin elasticity, and skin radiance were measured. The instrumental measurements were integrated by clinical analysis carried out by a board-certified dermatologist and by a self-assessment questionnaire carried out by each subject participating in the study.

RESULTS

After 28 days of product use the volume of the bags under the eye was decreased by 6.8% (p = 0.005), the dark circle color red and blue component improved by 7.1% (p = 0.001) and 4.0% (p = 0.001), respectively, wrinkle depth and skin roughness decreased by 15.8% (p = 0.001) and 6.3% (p = 0.011), respectively, skin moisturization increased by 11.7% (p = 0.000), the skin distensibility decreased by 8.9% (p = 0.000), the overall skin elasticity increased by 10.4% (p = 0.000), and the skin radiance increased by 16.3% (p = 0.000). The instrumental measured effects were also confirmed by the clinical analysis of the dermatologist and the self-assessment questionnaire output.

CONCLUSION

Conclusions: our results suggest that the test product is effective for periocular skin aesthetics (reduction of imperfections undermining the periocular area) and wellness.

摘要

目的

本研究旨在评估一种化妆品改善眼周皮肤外观的功效。

患者和方法

对40名有眼周皮肤衰老临床体征(包括眼袋和黑眼圈)的女性受试者进行了一项开放标签研究。在第0天和第28天测量眼袋体积、黑眼圈颜色、皮肤质地、皮肤水分、皮肤弹性和皮肤光泽。仪器测量结果通过一名获得委员会认证的皮肤科医生进行的临床分析以及参与研究的每位受试者填写的自我评估问卷进行综合。

结果

使用该产品28天后,眼袋体积减少了6.8%(p = 0.005),黑眼圈颜色的红色和蓝色成分分别改善了7.1%(p = 0.001)和4.0%(p = 0.001),皱纹深度和皮肤粗糙度分别降低了15.8%(p = 0.001)和6.3%(p = 0.011),皮肤水分增加了11.7%(p = 0.000),皮肤延展性降低了8.9%(p = 0.000),整体皮肤弹性增加了10.4%(p = 0.000),皮肤光泽增加了16.3%(p = 0.000)。仪器测量的效果也得到了皮肤科医生的临床分析和自我评估问卷结果的证实。

结论

我们的结果表明,该测试产品对眼周皮肤美容(减少损害眼周区域的瑕疵)和健康有益。

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