墨西哥出现间日疟原虫和登革热病毒对重症疟疾的罕见合并感染。

Unusual co-infection of severe malaria by Plasmodium vivax and dengue virus in Mexico.

作者信息

Queb-Pech N M, Núñez-Oreza L A, Estrada-Méndez A, Tamay-Segovia P, Collí-Heredia J P, Blum-Domínguez S C

机构信息

Departamento de Medicina Interna, Hospital General de Especialidades "Dr. Javier Buenfil Osorio", 24097 San Francisco de Campeche, Campeche, México.

Laboratorio de Microbiología y Biología Molecular, Centro de Investigaciones Biomédicas, Universidad Autónoma de Campeche, 24039 San Francisco de Campeche, Campeche, México.

出版信息

Trop Biomed. 2022 Dec 1;39(4):575-578. doi: 10.47665/tb.39.4.014.

DOI:10.47665/tb.39.4.014

PMID:36602218

Abstract

Malaria and dengue fever are among the most common mosquito-borne diseases worldwide; however, reports of coinfection are rare. We present a case of severe malaria and dengue coinfection in a 16-yearold female patient presenting with fever, thrombocytopenia, pleural effusion, myopericarditis, and acute respiratory distress syndrome. Dengue infection was confirmed by the presence of immunoglobin M antibodies and nonstructural protein 1, while malaria was confirmed by the presence of Plasmodium vivax in thick and thin blood smears. This is the first report of a dengue/malaria coinfection in Mexico.

摘要

疟疾和登革热是全球最常见的蚊媒疾病；然而，关于二者合并感染的报道却很罕见。我们报告了一例16岁女性患者同时感染重症疟疾和登革热的病例，该患者表现出发热、血小板减少、胸腔积液、心肌心包炎和急性呼吸窘迫综合征。通过免疫球蛋白M抗体和非结构蛋白1的检测确诊为登革热感染，而通过厚血膜和薄血膜中发现间日疟原虫确诊为疟疾感染。这是墨西哥首例登革热/疟疾合并感染的报告。