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Is dengue and malaria co-infection more severe than single infections? A retrospective matched-pair study in French Guiana.登革热和疟疾混合感染是否比单一感染更严重？法属圭亚那的一项回顾性配对研究。
Malar J. 2012 May 1;11:142. doi: 10.1186/1475-2875-11-142.
2
Risk factors and characterization of Plasmodium vivax-associated admissions to pediatric intensive care units in the Brazilian Amazon.巴西亚马逊地区儿科重症监护病房收治的间日疟原虫感染患者的风险因素和特征。
PLoS One. 2012;7(4):e35406. doi: 10.1371/journal.pone.0035406. Epub 2012 Apr 16.
3
Co-infection of Dengue virus by serotypes 3 and 4 in patients from Amazonas, Brazil.巴西亚马孙州患者中登革热病毒3型和4型的共同感染
Rev Inst Med Trop Sao Paulo. 2011 Nov-Dec;53(6):321-3. doi: 10.1590/s0036-46652011000600004.
4
Thrombocytopenia in malaria: who cares?疟疾相关性血小板减少症：谁在乎？
Mem Inst Oswaldo Cruz. 2011 Aug;106 Suppl 1:52-63. doi: 10.1590/s0074-02762011000900007.
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Urbanisation and infectious diseases in a globalised world.城市化与全球化世界中的传染病
Lancet Infect Dis. 2011 Feb;11(2):131-41. doi: 10.1016/S1473-3099(10)70223-1.
6
[Delayed diagnosis of malaria in a dengue endemic area in the Brazilian extra-Amazon: recent experience of a malaria surveillance unit in state of Rio de Janeiro].[巴西亚马孙地区以外登革热流行区疟疾的延迟诊断：里约热内卢州一个疟疾监测单位的近期经验]
Rev Soc Bras Med Trop. 2010 Sep-Oct;43(5):571-4. doi: 10.1590/s0037-86822010000500020.
7
Concurrent Dengue and malaria in the Amazon region.亚马逊地区同时出现登革热和疟疾。
Rev Soc Bras Med Trop. 2010 Sep-Oct;43(5):508-11. doi: 10.1590/s0037-86822010000500007.
8
Severe Plasmodium vivax malaria, Brazilian Amazon.严重的间日疟原虫疟疾，巴西亚马孙地区。
Emerg Infect Dis. 2010 Oct;16(10):1611-4. doi: 10.3201/eid1610.100685.
9
Allergies and diabetes as risk factors for dengue hemorrhagic fever: results of a case control study.过敏和糖尿病作为登革出血热的危险因素：病例对照研究的结果。
PLoS Negl Trop Dis. 2010 Jun 1;4(6):e699. doi: 10.1371/journal.pntd.0000699.
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Malaria in Brazil: an overview.巴西的疟疾：概述。
Malar J. 2010 Apr 30;9:115. doi: 10.1186/1475-2875-9-115.

巴西亚马逊地区同时患有登革热和间日疟原虫疟疾的临床特征：11 例住院患者的病例系列。

Clinical profile of concurrent dengue fever and Plasmodium vivax malaria in the Brazilian Amazon: case series of 11 hospitalized patients.

机构信息

Universidade do Estado do Amazonas, Manaus, Brazil.

出版信息

Am J Trop Med Hyg. 2012 Dec;87(6):1119-24. doi: 10.4269/ajtmh.2012.12-0210. Epub 2012 Oct 1.

DOI:10.4269/ajtmh.2012.12-0210
PMID:23033396
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3516086/
Abstract

Malaria and dengue fever are the most prevalent vector-borne diseases worldwide. This study aims to describe the clinical profile of patients with molecular diagnosis of concurrent malaria and dengue fever in a tropical-endemic area. Eleven patients with concurrent dengue virus (DENV) and Plasmodium vivax infection are reported. Similar frequencies of DENV-2, DENV-3, and DENV-4 were found, including DENV-3/DENV-4 co-infection. In eight patients, the World Health Organization (WHO) criteria for severe malaria could be fulfilled (jaundice being the most common). Only one patient met severe dengue criteria, but warning signs were present in 10. Syndromic surveillance systems must be ready to identify this condition to avoid misinterpretation of severity attributed to a single disease.

摘要

疟疾和登革热是全球最普遍的虫媒传染病。本研究旨在描述热带流行地区经分子诊断为同时感染疟疾和登革热患者的临床特征。报告了 11 例登革病毒（DENV）和间日疟原虫混合感染的患者。发现 DENV-2、DENV-3 和 DENV-4 的频率相似，包括 DENV-3/DENV-4 共同感染。在 8 例患者中，符合世界卫生组织（WHO）重症疟疾标准（黄疸是最常见的）。只有 1 例患者符合重症登革热标准，但 10 例患者存在预警信号。症状监测系统必须做好准备识别这种情况，以避免因单一疾病而导致的严重程度的误解。