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低蛋白血症作为减重手术翻修/转换术并发症的风险因素:MBSAQIP 分析。

Hypoalbuminemia as a risk factor for complications in revisional/conversional bariatric surgery: an MBSAQIP analysis.

机构信息

Department of Surgery, University of Missouri School of Medicine, Columbia, Missouri.

Department of Surgery, University of Missouri School of Medicine, Columbia, Missouri.

出版信息

Surg Obes Relat Dis. 2023 Jun;19(6):555-561. doi: 10.1016/j.soard.2022.12.010. Epub 2022 Dec 9.

Abstract

BACKGROUND

Hypoalbuminemia (HA) is a risk factor for serious complications after elective bariatric surgery. Patients undergoing revisional/conversional bariatric surgery may represent a higher-risk group who often have underlying co-morbid medical illnesses and more complex surgery.

OBJECTIVES

This study investigated the postoperative complications in patients with HA undergoing revisional/conversional bariatric surgery.

SETTING

Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP), years 2015-2019.

METHODS

The MBSAQIP database was used to evaluate patients undergoing non-banding revisional/conversional bariatric surgery between 2015 and 2019. Patients were categorized by serum albumin (≤3.5 g/dL). Variables were assessed via bivariate analysis and multivariable regression. Propensity score matching was conducted to compare gastric bypass (RYGB) to sleeve gastrectomy (VSG).

RESULTS

One hundred forty-seven thousand four hundred thirty patients underwent revisional/conversional procedures. After applied exclusions, 58,777 patients were available for analysis. The HA group had a significantly (P < .05) higher prevalence of being black (22.95% versus 17.76%), renal insufficiency (1.08% versus .36%), smoking history (9.47% versus 6.91%), chronic obstructive pulmonary disease (COPD) (2.54% versus 1.33%), and history of deep vein thrombosis (DVT) (4.03% versus 2.3%). Postoperative complications associated with HA included perioperative blood transfusion (3.1% versus 1.27%; P < .001), 30day readmission (10.87 versus 6.77%; P < .001), 30day reoperation (4.9% versus 3.18%; P < .001), and 30day mortality (.40% versus .14%; P < .0001). HA was a significant predictor of 30day readmission in the RYGB versus VSG matched cohort (odds ratio [OR], 1.30; 95% confidence interval [CI], [1.14, 1.48]; P < .001).

CONCLUSIONS

HA is a risk factor requiring attention for patients undergoing revisional/conversional bariatric surgery and optimization of nutritional status or medical comorbidities associated with HA prior to bariatric surgery may help avoid postoperative complications.

摘要

背景

低蛋白血症(HA)是择期减重手术后发生严重并发症的一个危险因素。接受修正/转换减重手术的患者可能代表了一个更高风险的群体,他们通常有潜在的合并症和更复杂的手术。

目的

本研究调查了接受修正/转换减重手术的 HA 患者的术后并发症。

设置

代谢和减重外科认证和质量改进计划(MBSAQIP),2015-2019 年。

方法

使用 MBSAQIP 数据库评估 2015 年至 2019 年间接受非带修正/转换减重手术的患者。根据血清白蛋白(≤3.5g/dL)对患者进行分类。通过双变量分析和多变量回归评估变量。进行倾向评分匹配以比较胃旁路术(RYGB)和袖状胃切除术(VSG)。

结果

147430 例患者接受了修正/转换手术。经过排除,58777 例患者可供分析。HA 组黑人的比例明显更高(22.95% vs. 17.76%),肾功能不全(1.08% vs. 0.36%)、吸烟史(9.47% vs. 6.91%)、慢性阻塞性肺疾病(COPD)(2.54% vs. 1.33%)和深静脉血栓形成(DVT)病史(4.03% vs. 2.3%)。与 HA 相关的术后并发症包括围手术期输血(3.1% vs. 1.27%;P<0.001)、30 天再入院(10.87% vs. 6.77%;P<0.001)、30 天再次手术(4.9% vs. 3.18%;P<0.001)和 30 天死亡率(0.40% vs. 0.14%;P<0.0001)。HA 是 RYGB 与 VSG 匹配队列中 30 天再入院的显著预测因素(比值比[OR],1.30;95%置信区间[CI],[1.14,1.48];P<0.001)。

结论

HA 是接受修正/转换减重手术患者需要关注的一个危险因素,在减重手术前优化与 HA 相关的营养状况或合并症可能有助于避免术后并发症。

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