Department of Surgery, University of Missouri School of Medicine, Columbia, Missouri.
Department of Surgery, University of Missouri School of Medicine, Columbia, Missouri.
Surg Obes Relat Dis. 2023 Jun;19(6):555-561. doi: 10.1016/j.soard.2022.12.010. Epub 2022 Dec 9.
Hypoalbuminemia (HA) is a risk factor for serious complications after elective bariatric surgery. Patients undergoing revisional/conversional bariatric surgery may represent a higher-risk group who often have underlying co-morbid medical illnesses and more complex surgery.
This study investigated the postoperative complications in patients with HA undergoing revisional/conversional bariatric surgery.
Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP), years 2015-2019.
The MBSAQIP database was used to evaluate patients undergoing non-banding revisional/conversional bariatric surgery between 2015 and 2019. Patients were categorized by serum albumin (≤3.5 g/dL). Variables were assessed via bivariate analysis and multivariable regression. Propensity score matching was conducted to compare gastric bypass (RYGB) to sleeve gastrectomy (VSG).
One hundred forty-seven thousand four hundred thirty patients underwent revisional/conversional procedures. After applied exclusions, 58,777 patients were available for analysis. The HA group had a significantly (P < .05) higher prevalence of being black (22.95% versus 17.76%), renal insufficiency (1.08% versus .36%), smoking history (9.47% versus 6.91%), chronic obstructive pulmonary disease (COPD) (2.54% versus 1.33%), and history of deep vein thrombosis (DVT) (4.03% versus 2.3%). Postoperative complications associated with HA included perioperative blood transfusion (3.1% versus 1.27%; P < .001), 30day readmission (10.87 versus 6.77%; P < .001), 30day reoperation (4.9% versus 3.18%; P < .001), and 30day mortality (.40% versus .14%; P < .0001). HA was a significant predictor of 30day readmission in the RYGB versus VSG matched cohort (odds ratio [OR], 1.30; 95% confidence interval [CI], [1.14, 1.48]; P < .001).
HA is a risk factor requiring attention for patients undergoing revisional/conversional bariatric surgery and optimization of nutritional status or medical comorbidities associated with HA prior to bariatric surgery may help avoid postoperative complications.
低蛋白血症(HA)是择期减重手术后发生严重并发症的一个危险因素。接受修正/转换减重手术的患者可能代表了一个更高风险的群体,他们通常有潜在的合并症和更复杂的手术。
本研究调查了接受修正/转换减重手术的 HA 患者的术后并发症。
代谢和减重外科认证和质量改进计划(MBSAQIP),2015-2019 年。
使用 MBSAQIP 数据库评估 2015 年至 2019 年间接受非带修正/转换减重手术的患者。根据血清白蛋白(≤3.5g/dL)对患者进行分类。通过双变量分析和多变量回归评估变量。进行倾向评分匹配以比较胃旁路术(RYGB)和袖状胃切除术(VSG)。
147430 例患者接受了修正/转换手术。经过排除,58777 例患者可供分析。HA 组黑人的比例明显更高(22.95% vs. 17.76%),肾功能不全(1.08% vs. 0.36%)、吸烟史(9.47% vs. 6.91%)、慢性阻塞性肺疾病(COPD)(2.54% vs. 1.33%)和深静脉血栓形成(DVT)病史(4.03% vs. 2.3%)。与 HA 相关的术后并发症包括围手术期输血(3.1% vs. 1.27%;P<0.001)、30 天再入院(10.87% vs. 6.77%;P<0.001)、30 天再次手术(4.9% vs. 3.18%;P<0.001)和 30 天死亡率(0.40% vs. 0.14%;P<0.0001)。HA 是 RYGB 与 VSG 匹配队列中 30 天再入院的显著预测因素(比值比[OR],1.30;95%置信区间[CI],[1.14,1.48];P<0.001)。
HA 是接受修正/转换减重手术患者需要关注的一个危险因素,在减重手术前优化与 HA 相关的营养状况或合并症可能有助于避免术后并发症。