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[疱疹性角膜炎患者外周血淋巴细胞的氧化还原酶活性]

[Oxidoreductase activity of peripheral blood lymphocytes of patients with herpetic keratitis].

作者信息

Petrovich Iu A, Terekhina N A, Gol'dfel'd N G

出版信息

Vopr Med Khim. 1987 Jul-Aug;33(4):59-61.

PMID:3660741
Abstract

Activities of glutathione peroxidase, lactate-, malate- and glutamate dehydrogenases were decreased, while glucose-6-phosphate dehydrogenase was activated in peripheric blood lymphocytes of patients with herpetic keratitis within the acute period. Alterations in the enzymatic activity were especially distinct in herpetic ulcer of sclera as compared with other clinical forms of herpetic keratitis. As lymphocyte oxidoreductases responded distinctly to herpetic infection, estimation of their activity could be used for diagnosis, prognosis and monitoring of herpes treatment.

摘要

在急性期,疱疹性角膜炎患者外周血淋巴细胞中的谷胱甘肽过氧化物酶、乳酸脱氢酶、苹果酸脱氢酶和谷氨酸脱氢酶的活性降低,而葡萄糖-6-磷酸脱氢酶被激活。与疱疹性角膜炎的其他临床形式相比,酶活性的改变在巩膜疱疹性溃疡中尤为明显。由于淋巴细胞氧化还原酶对疱疹感染有明显反应,对其活性的评估可用于疱疹的诊断、预后和治疗监测。

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