[眼部单纯疱疹病毒感染中抗氧化酶活性及外周血淋巴细胞化学发光情况]
[Activity of antioxidant enzymes and peripheral blood lymphocyte chemiluminescence in herpes simplex virus infection of the eye].
作者信息
Terekhina N A, Petrovich Iu A
出版信息
Vopr Med Khim. 1992 Sep-Oct;38(5):62-3.
PMID:1337229
Abstract
Activation of lipid peroxidation in ophthalmic herpes may be estimated by an increase in the rate of chemoluminescence in peripheral lymphocytes within 2, 5-7 and 14 days after injection of herpes simplex virus into the rabbit retina. In the peripheral lymphocytes of patients with naturally developed herpetic keratitis the activity of glutathione peroxidase was decreased, while that of superoxide dismutase was increased 2-2.5-fold in the ophthalmic herpes as compared with the normal state.
摘要
将单纯疱疹病毒注入兔视网膜后2天、5 - 7天和14天，可通过外周淋巴细胞化学发光速率的增加来估计眼部疱疹中脂质过氧化的激活情况。在自然发生疱疹性角膜炎患者的外周淋巴细胞中，谷胱甘肽过氧化物酶的活性降低，而与正常状态相比，眼部疱疹中超氧化物歧化酶的活性增加了2 - 2.5倍。
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