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α肾上腺素能受体阻滞剂对子宫收缩的抑制作用

[Inhibition of uterine contractions by alpha adrenergic receptor blockaders].

作者信息

Lechner W, Daxenbichler G, Marth C

机构信息

Universitätsklinik für Frauenheilkunde Innsbruck.

出版信息

Z Geburtshilfe Perinatol. 1987 May-Jun;191(3):102-4.

PMID:3660905
Abstract

In order to further investigate the adrenergic system of the pregnant uterus, the alpha 2-adrenoblocker Yohimbine and the alpha 1-alpha 2-blocker Phentolamine were examined in regard to their tocolytic effect on myometrial strips and compared with the relaxant effect of Prazosin which was already detected by our group. For both substances a highly significant decrease of uterine activity was found which did not differ from that of the alpha 1-blocker Prazosin.

摘要

为了进一步研究妊娠子宫的肾上腺素能系统,对α2-肾上腺素能阻滞剂育亨宾和α1-α2阻滞剂酚妥拉明对子宫肌条的宫缩抑制作用进行了检测,并与本研究组已检测到的哌唑嗪的松弛作用进行了比较。发现这两种物质均可使子宫活动显著降低,且与α1阻滞剂哌唑嗪的作用无差异。

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