Aroca-Martinez Gustavo, Hernandez-Agudelo Sandra, Castro-Hernández Christian, Cabarcas-Barbosa Omar, Terrasa Sergio Adrián, González-Torres Henry J, Cadena-Bonfanti Andrés, Musso Carlos G
Universidad del Norte, Barranquilla, Colombia.
Facultad de Ciencias de la Salud, Universidad Simón Bolívar, Barranquilla, Colombia.
Ir J Med Sci. 2023 Oct;192(5):2501-2505. doi: 10.1007/s11845-022-03264-8. Epub 2023 Jan 7.
Frailty is a clinical syndrome characterized by a decrease in strength, resistance and body physiological condition, making the individual more vulnerable, and increasing his/her risk of dependence and death. Kidney transplant (KT) is currently the best end-stage renal disease therapeutic alternative for certain individuals. Frailty status occurs in approximately 20% of KT patients. Thus, it was evaluated if there would be any change in frailty status level in a population of adult patients on chronic HD after receiving KT.
A cross-sectional study was conducted on a population of adult hemodialysis patients (n: 57), with the objective of evaluating if there was a significant change in their clinical frailty score (CFS) after 6 months of KT. For the statistical analysis, the Student's t-test, and the test of statistical significance between two proportions were applied.
Mean CFS before KT was 4 (vulnerable), and after KT was 3 (robust). CFS value was significantly lower after KT (p value < 0.01).
A significant improvement was found between pre- and post-transplant clinical frailty scores in hemodialysis adult patients.
衰弱是一种临床综合征，其特征是力量、抵抗力和身体生理状况下降，使个体更容易受到伤害，并增加其依赖和死亡的风险。肾移植（KT）目前是某些个体终末期肾病的最佳治疗选择。约20%的KT患者存在衰弱状态。因此，本研究评估了接受KT后的成年慢性血液透析患者群体的衰弱状态水平是否会发生变化。
对成年血液透析患者群体（n = 57）进行了一项横断面研究，目的是评估KT 6个月后其临床衰弱评分（CFS）是否有显著变化。统计分析采用学生t检验和两个比例之间的统计学显著性检验。
KT前CFS平均值为4（脆弱），KT后为3（强健）。KT后CFS值显著降低（p值<0.01）。
血液透析成年患者移植前和移植后的临床衰弱评分有显著改善。
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