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心脏骤停后:机制、管理及未来展望

Post-Cardiac Arrest: Mechanisms, Management, and Future Perspectives.

作者信息

Lazzarin Taline, Tonon Carolina Rodrigues, Martins Danilo, Fávero Edson Luiz, Baumgratz Thiago Dias, Pereira Filipe Welson Leal, Pinheiro Victor Rocha, Ballarin Raquel Simões, Queiroz Diego Aparecido Rios, Azevedo Paula Schmidt, Polegato Bertha Furlan, Okoshi Marina Politi, Zornoff Leonardo, Rupp de Paiva Sergio Alberto, Minicucci Marcos Ferreira

机构信息

Internal Medicine Department, Botucatu Medical School, Universidade Estadual Paulista (UNESP), Botucatu 18607-741, Brazil.

出版信息

J Clin Med. 2022 Dec 29;12(1):259. doi: 10.3390/jcm12010259.

Abstract

Cardiac arrest is an important public health issue, with a survival rate of approximately 15 to 22%. A great proportion of these deaths occur after resuscitation due to post-cardiac arrest syndrome, which is characterized by the ischemia-reperfusion injury that affects the role body. Understanding physiopathology is mandatory to discover new treatment strategies and obtain better results. Besides improvements in cardiopulmonary resuscitation maneuvers, the great increase in survival rates observed in recent decades is due to new approaches to post-cardiac arrest care. In this review, we will discuss physiopathology, etiologies, and post-resuscitation care, emphasizing targeted temperature management, early coronary angiography, and rehabilitation.

摘要

心脏骤停是一个重要的公共卫生问题,其生存率约为15%至22%。这些死亡中有很大一部分发生在复苏后,原因是心脏骤停后综合征,其特征是影响全身的缺血再灌注损伤。了解病理生理学对于发现新的治疗策略并取得更好的结果至关重要。除了心肺复苏操作的改进外,近几十年来观察到的生存率大幅提高归因于心脏骤停后护理的新方法。在这篇综述中,我们将讨论病理生理学、病因以及复苏后护理,重点强调目标温度管理、早期冠状动脉造影和康复治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42fd/9820907/b0e43eea6b9f/jcm-12-00259-g001.jpg

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