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婴儿双胞胎体重和身长的遗传变异

Genetic variance of weight and length in infant twins.

作者信息

Levine R S, Hennekens C H, Jesse M J

机构信息

Dept. of Epidemiology, U. of Miami, FL 33101.

出版信息

Am J Epidemiol. 1987 Nov;126(5):929-35. doi: 10.1093/oxfordjournals.aje.a114730.

DOI:10.1093/oxfordjournals.aje.a114730
PMID:3661540
Abstract

A population-based cohort of 166 twin pairs (67 monozygotic and 99 dizygotic) born at the Jackson Memorial Hospital/University of Miami Medical Center, from July 1, 1976 to December 31, 1980 was identified. Body weight and length were measured at 14 days and at one, three, six, nine, and 12 months of age. Statistically significant genetic variance was found for both body weight and length at each data point. Heritability for body weight increased from 0.28 at 14 days to 0.64 at one year. Corresponding values for body length were 0.16 and 0.48.

摘要

确定了一个基于人群的队列,其中包括1976年7月1日至1980年12月31日在杰克逊纪念医院/迈阿密大学医学中心出生的166对双胞胎(67对同卵双胞胎和99对异卵双胞胎)。在出生后14天以及1、3、6、9和12个月时测量体重和身长。在每个数据点,体重和身长均发现有统计学意义的遗传方差。体重的遗传率从14天时的0.28增加到1岁时的0.64。身长的相应值分别为0.16和0.48。

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