Mansikka Iisa, Kinnunen Ilpo, Hirvonen Jussi, Vainio Paula, Velhonoja Jarno
Department of Otorhinolaryngology and Head and Neck Surgery Turku University Hospital and University of Turku Turku Finland.
Department of Radiology Turku University Hospital and University of Turku Turku Finland.
Clin Case Rep. 2023 Jan 6;11(1):e6817. doi: 10.1002/ccr3.6817. eCollection 2023 Jan.
Metastases of distant primary tumors on the parotid gland are very rare. Tumor-to-tumor metastasis to salivary gland tumors is extremely rare. A case of a 69-year-old woman with a large left parotid gland mass with no previous salivary gland problems or cancer. Fine-needle aspiration (FNA) showed evidence of a Warthin tumor. A total left parotidectomy was performed. The final pathology report showed a Warthin tumor containing two metastases of adenocarcinoma. The immunohistochemistry of the metastases led to the diagnosis of primary breast cancer. A negative FNA does not rule out the possibility of a malignant parotid tumor or metastasis, and a parotid lump should be presumed to be a secondary tumor until proven otherwise if the patient has a history of any distant primary cancer. Our patient case serves as a reminder that a new distant primary cancer might be the cause of a parotid lump.
远处原发性肿瘤转移至腮腺极为罕见。肿瘤之间的转移至涎腺肿瘤极其罕见。一名69岁女性,左侧腮腺有一巨大肿块,既往无涎腺问题或癌症病史。细针穿刺活检(FNA)显示为沃辛瘤。遂行左侧腮腺全切除术。最终病理报告显示沃辛瘤伴腺癌两处转移。转移灶的免疫组化检查确诊为原发性乳腺癌。FNA结果为阴性并不能排除腮腺恶性肿瘤或转移的可能性,若患者有任何远处原发性癌症病史,在未证实其他情况之前,应假定腮腺肿块为继发性肿瘤。我们的患者病例提醒我们,新出现的远处原发性癌症可能是腮腺肿块的病因。