Chan F, Orsbon S
Health Science Department, College of Health Professions, Wichita State University, KS 67208.
Anat Rec. 1987 Aug;218(4):446-9. doi: 10.1002/ar.1092180413.
This experiment was designed to study the effect of optic nerve denervation on lens regeneration. Adult newts, Triturus viridescens, were divided into 4 groups: A) lentectomized newts, which served as controls, B) lentectomized newts with the optic nerve exposed and lightly palpated, C) newts with lens removed and the optic nerve cut simultaneously, and D) newts with lens removed first and optic nerve cut 7 days and 14 days later. Control animals required about 21 days to produce a new lens, and animals in group B demonstrated the same regeneration rate. In groups C and D, the regeneration rate was greatly retarded during the first 14 days. However, most of these animals regenerated a perfect new lens by 21 days postlentectomy.
本实验旨在研究视神经去神经支配对晶状体再生的影响。成年绿螈被分为4组:A)晶状体切除的绿螈作为对照组;B)晶状体切除且视神经暴露并轻轻触摸的绿螈;C)晶状体切除同时切断视神经的绿螈;D)先切除晶状体,7天和14天后切断视神经的绿螈。对照动物大约需要21天来生成一个新的晶状体,B组动物表现出相同的再生率。在C组和D组中,在前14天再生率大大延迟。然而,这些动物中的大多数在晶状体切除后21天时再生出了完美的新晶状体。