Jiang Yuxiang, Tan Zhuomin, Zhao Tianshu, Wu Jiajia, Li Ya, Jia Yinnong, Peng Zhili
Yunnan Key Laboratory for Micro/Nano Materials & Technology, School of Materials and Energy, Yunnan University, Kunming 650091, People's Republic of China.
Yunnan Provincial Key Laboratory of Pharmacology for Natural Products, School of Pharmaceutical Sciences, Kunming Medical University, Kunming 650500, People's Republic of China.
Nanoscale. 2023 Jan 27;15(4):1925-1936. doi: 10.1039/d2nr06058b.
A simple yet effective strategy to enhance the properties of traditional dye indocyanine green (ICG) in all aspects was proposed and demonstrated. Specifically, indocyanine green-derived carbon dots (ICGCDs) were synthesized from ICG a simple hydrothermal treatment. The ICGCDs exhibited significantly enhanced thermal stability and anti-photobleaching compared to ICG. Furthermore, their photothermal properties were also notably strengthened, in which a wider functional pH range, 50% improvement in photothermal conversion efficiency and superior photothermal cyclability were achieved. Thanks to these superior properties, ICGCDs were demonstrated as efficient NIR bioimaging and photothermal agents in both and experiments. Most excitingly, the strategy demonstrated in this study is likely to have broad applications in other systems.
提出并证明了一种简单而有效的策略，可在各个方面增强传统染料吲哚菁绿（ICG）的性能。具体而言，通过简单的水热处理从ICG合成了吲哚菁绿衍生的碳点（ICGCDs）。与ICG相比，ICGCDs表现出显著增强的热稳定性和抗光漂白性能。此外，它们的光热性能也得到了显著增强，实现了更宽的功能性pH范围、50%的光热转换效率提高和优异的光热循环性。由于这些优异的性能，ICGCDs在体内和体外实验中均被证明是有效的近红外生物成像和光热剂。最令人兴奋的是，本研究中展示的策略可能在其他系统中具有广泛的应用。
