• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

往返之旅:50 年探索未知的 Fusorum 之地。

There and back again: 50 years of wandering through terra incognita fusorum.

机构信息

Department of Biosciences, University of Durham, Durham, UK.

Biophysical Sciences Institute, University of Durham, Durham, UK.

出版信息

Exp Physiol. 2024 Jan;109(1):6-16. doi: 10.1113/EP090760. Epub 2023 Jan 11.

DOI:10.1113/EP090760
PMID:36628601
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10988739/
Abstract

This paper is in two parts: 'There', which is a review of some of the major advances in the study of spindle structure and function during the past 50 years, serving as an introduction to the symposium entitled 'Mechanotransduction, Muscle Spindles and Proprioception' held in Munich in July 2022; and 'And Back Again', presenting new quantitative morphological results on the equatorial nuclei of intrafusal muscle fibres and of the primary sensory ending in relationship to passive stretch of the spindle.

摘要

本文分为两部分

“There”,回顾了过去 50 年来在纺锤体结构和功能研究方面的一些主要进展,作为 2022 年 7 月在慕尼黑举行的题为“机械转导、肌肉纺锤体和本体感受”研讨会的介绍;和“又回来了”,介绍了关于肌梭内纤维赤道核和初级感觉末梢与纺锤体被动拉伸相关的新的定量形态学结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/a108608e3349/EPH-109-6-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/2a24f980dcc5/EPH-109-6-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/01946c45a9c2/EPH-109-6-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/2c8a49e0b3de/EPH-109-6-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/5a62e734d7e5/EPH-109-6-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/1dce984f66a1/EPH-109-6-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/2fc9bea58b05/EPH-109-6-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/64c9b0e36406/EPH-109-6-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/1766beb003a1/EPH-109-6-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/a108608e3349/EPH-109-6-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/2a24f980dcc5/EPH-109-6-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/01946c45a9c2/EPH-109-6-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/2c8a49e0b3de/EPH-109-6-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/5a62e734d7e5/EPH-109-6-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/1dce984f66a1/EPH-109-6-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/2fc9bea58b05/EPH-109-6-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/64c9b0e36406/EPH-109-6-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/1766beb003a1/EPH-109-6-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62cc/10988739/a108608e3349/EPH-109-6-g006.jpg

相似文献

1
There and back again: 50 years of wandering through terra incognita fusorum.往返之旅:50 年探索未知的 Fusorum 之地。
Exp Physiol. 2024 Jan;109(1):6-16. doi: 10.1113/EP090760. Epub 2023 Jan 11.
2
Acetylcholine receptors in the equatorial region of intrafusal muscle fibres modulate mouse muscle spindle sensitivity.肌梭内纤维赤道区的乙酰胆碱受体调节小鼠肌梭敏感性。
J Physiol. 2019 Apr;597(7):1993-2006. doi: 10.1113/JP277139. Epub 2019 Feb 13.
3
Structure, distribution and innervation of muscle spindles in avian fast and slow skeletal muscle.禽类快、慢骨骼肌中肌梭的结构、分布及神经支配
J Anat. 1999 Apr;194 ( Pt 3)(Pt 3):381-94. doi: 10.1046/j.1469-7580.1999.19430381.x.
4
Existence of a muscle spindle on the posterior cricoarytenoid muscle of the guinea pig.豚鼠环杓后肌上肌梭的存在。
J Electron Microsc (Tokyo). 1997;46(3):257-61. doi: 10.1093/oxfordjournals.jmicro.a023518.
5
A novel muscle spindle containing muscle fibres devoid of sensory innervation in the posterior cricoarytenoid muscle of the normal adult guinea pig.在正常成年豚鼠的环杓后肌中,一种新型肌梭包含无感觉神经支配的肌纤维。
J Electron Microsc (Tokyo). 1998;47(1):81-5. doi: 10.1093/oxfordjournals.jmicro.a023562.
6
The response of fast and slow nuclear bag fibres and nuclear chain fibres in isolated cat muscle spindles to fusimotor stimulation, and the effect of intrafusal contraction on the sensory endings.分离的猫肌梭中快、慢核袋纤维和核链纤维对梭内肌运动神经刺激的反应,以及肌梭内收缩对感觉末梢的影响。
Q J Exp Physiol Cogn Med Sci. 1976 Jul;61(3):203-54. doi: 10.1113/expphysiol.1976.sp002354.
7
Egr3-dependent muscle spindle stretch receptor intrafusal muscle fiber differentiation and fusimotor innervation homeostasis.Egr3依赖的肌梭牵张感受器梭内肌纤维分化和运动神经支配稳态。
J Neurosci. 2015 Apr 8;35(14):5566-78. doi: 10.1523/JNEUROSCI.0241-15.2015.
8
Intrafusal cross-bridge dynamics shape history-dependent muscle spindle responses to stretch.肌梭对牵张刺激的依赖史依赖性反应受梭内横桥动力学的影响。
Exp Physiol. 2024 Jan;109(1):112-124. doi: 10.1113/EP090767. Epub 2023 Jul 10.
9
Expression of myosin heavy chain isoforms in regenerated muscle spindle fibres after muscle grafting in young and adult rats--plasticity of intrafusal satellite cells.幼年和成年大鼠肌肉移植后再生肌梭纤维中肌球蛋白重链亚型的表达——梭内卫星细胞的可塑性
Differentiation. 1997 Dec;62(4):179-86. doi: 10.1046/j.1432-0436.1998.6240179.x.
10
Primary and secondary afferent discharges from the same spindle during chain fibre contraction in cat tenuissimus muscle.猫薄肌链纤维收缩期间,来自同一梭内肌的初级和次级传入放电。
Exp Physiol. 1994 Sep;79(5):691-704. doi: 10.1113/expphysiol.1994.sp003801.

引用本文的文献

1
Experimental Physiology special issue: 'Mechanotransduction, muscle spindles and proprioception'.《实验生理学》特刊:“机械转导、肌梭与本体感觉”
Exp Physiol. 2024 Jan;109(1):1-5. doi: 10.1113/EP091431. Epub 2023 Dec 31.
2
Sensorimotor control in the congenital absence of functional muscle spindles.先天性功能性肌梭缺失的运动感觉控制。
Exp Physiol. 2024 Jan;109(1):27-34. doi: 10.1113/EP090768. Epub 2023 Apr 8.
3
Knee movements cause changes in the firing behaviour of muscle spindles located within the mono-articular ankle extensor soleus in the rat.

本文引用的文献

1
Spindles are doin' it for themselves: Glutamatergic autoexcitation in muscle spindles.肌梭自行其是:肌梭中的谷氨酸能自激作用
J Physiol. 2021 Jun;599(11):2781-2783. doi: 10.1113/JP281624. Epub 2021 May 10.
2
Molecular correlates of muscle spindle and Golgi tendon organ afferents.肌肉梭和高尔基腱器官传入的分子相关性。
Nat Commun. 2021 Mar 1;12(1):1451. doi: 10.1038/s41467-021-21880-3.
3
Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice.本体感觉背根神经节神经元的不同亚型调节小鼠的适应性本体感觉。
膝关节运动引起位于大鼠单关节踝伸肌比目鱼肌内的肌梭放电行为的变化。
Exp Physiol. 2024 Jan;109(1):125-134. doi: 10.1113/EP090764. Epub 2023 Feb 24.
Nat Commun. 2021 Feb 15;12(1):1026. doi: 10.1038/s41467-021-21173-9.
4
Single-nucleus transcriptomics reveals functional compartmentalization in syncytial skeletal muscle cells.单细胞转录组学揭示了合胞体骨骼肌细胞中的功能区隔化。
Nat Commun. 2020 Dec 11;11(1):6375. doi: 10.1038/s41467-020-20064-9.
5
Fibre typing of intrafusal fibres.梭内肌纤维的纤维类型划分
J Anat. 2015 Aug;227(2):136-56. doi: 10.1111/joa.12338.
6
The innervation of the muscle spindle: a personal history.肌梭的神经支配:个人经历。
J Anat. 2015 Aug;227(2):115-35. doi: 10.1111/joa.12297. Epub 2015 Jun 19.
7
Mechanotransduction in the muscle spindle.肌梭中的机械转导
Pflugers Arch. 2015 Jan;467(1):175-90. doi: 10.1007/s00424-014-1536-9. Epub 2014 Jun 3.
8
An allometric analysis of the number of muscle spindles in mammalian skeletal muscles.哺乳动物骨骼肌中肌梭数量的异速生长分析。
J Anat. 2006 Jun;208(6):753-68. doi: 10.1111/j.1469-7580.2006.00558.x.
9
Reconstruct: a free editor for serial section microscopy.Reconstruct:一款用于连续切片显微镜检查的免费编辑器。
J Microsc. 2005 Apr;218(Pt 1):52-61. doi: 10.1111/j.1365-2818.2005.01466.x.
10
MUSCLE SPINDLES AND THEIR MOTOR CONTROL.肌梭及其运动控制
Physiol Rev. 1964 Apr;44:219-88. doi: 10.1152/physrev.1964.44.2.219.