Carazo-Barrios L, Gallardo-Tur A, Aguilar-Monge A, Heras-González M L, Sempere-Fernández J F, Hamad-Cueto O, Heras-Pérez J A, de la Cruz-Cosme C
Hospital Universitario Virgen de la Victoria, 29010 Málaga, España.
Rev Neurol. 2023 Jan 16;76(2):47-57. doi: 10.33588/rn.7602.2022131.
The nationwide lockdown implemented in Spain in March 2020 in response to the 2019 coronavirus disease pandemic (COVID-19) could have had an effect on the clinical situation, disease management and access to care in patients with idiopathic intracranial hypertension.
A cross-sectional observational study was conducted by means of an online survey. The frequency and impact of headache, visual symptoms, dizziness, cognitive symptoms, diplopia, anxiety and depression on patients' quality of life were recorded. Disease treatment and delays experienced in accessing care were recorded. Participants were grouped according to the time elapsed since diagnosis.
A total of 112 patients participated in the study (103 women). The average time since disease onset was 6.25 years. Headache, anxiety and depression were responsible for considerable impact in the period prior to lockdown. The impact of headache was not aggravated during lockdown, but anxiety and depression did become significantly worse. Recently diagnosed participants reported higher rates of anxiety, depression, dizziness and diplopia; chronically diagnosed participants reported a higher frequency of cognitive symptoms.
The clinical situation of the participants deteriorated during lockdown, although the differences were smaller than previously thought. This was probably because the baseline situation was more severe than expected. Further studies are needed to clarify the medium and long-term impact of the COVID-19 pandemic on patients with idiopathic intracranial hypertension.
2020年3月西班牙为应对2019冠状病毒病大流行（COVID-19）而实施的全国封锁可能对特发性颅内高压患者的临床状况、疾病管理及医疗服务可及性产生影响。
通过在线调查开展一项横断面观察性研究。记录头痛、视觉症状、头晕、认知症状、复视、焦虑和抑郁对患者生活质量的发生频率及影响。记录疾病治疗情况及就医时经历的延误。参与者根据诊断后的时间分组。
共有112名患者参与研究（103名女性）。自疾病发作以来的平均时间为6.25年。在封锁前，头痛、焦虑和抑郁造成了相当大的影响。封锁期间头痛的影响未加重，但焦虑和抑郁确实明显恶化。近期确诊的参与者报告焦虑、抑郁、头晕和复视的发生率更高；长期确诊的参与者报告认知症状的发生频率更高。
尽管差异比之前认为的小，但封锁期间参与者的临床状况恶化。这可能是因为基线情况比预期更严重。需要进一步研究以阐明COVID-19大流行对特发性颅内高压患者的中长期影响。
