Kong Chi Wah, Chiu Tin Lok, Cheung Chi Wai, Lee Tsz Yan, Yeung Fu Ki, Yu Siu Ki
Medical Physics Department, Hong Kong Sanatorium and Hospital, Hong Kong SAR, China.
Rep Pract Oncol Radiother. 2022 Dec 29;27(6):1106-1113. doi: 10.5603/RPOR.a2022.0111. eCollection 2022.
The objective was to investigate the change in segmentation error of Radixact Synchrony lung treatment after its kV imaging system was upgraded from Generation 1 to Generation 2 in the ClearRT™ installation.
Radixact Lung Synchrony plans were created for the Model 18023 Xsight Lung Tracking "XLT" Phantom combined with different lung target inserts with densities of 0.280, 0.500, 0.943 and 1.093 g/cc. After Radixact Synchrony treatment delivery using the Generation 1 and Generation 2 kV systems according to each plan, the tracking performance of the two kV systems on each density insert was compared by calculating the root mean square (RMS) error (δ) between the Synchrony-predicted motion in the log file and the known phantom motion and by calculating δ95%, the maximum error within a 95% probability threshold.
The δ and δ95% of Radixact Synchrony treatment for Gen1 kV systems deteriorated as the density of the target insert decreased, from 1.673 ± 0.064 mm and 3.049 ± 0.089 mm, respectively, for the 1.093 g/cc insert to 8.355 ± 5.873 mm and 15.297 ± 10.470 mm, respectively, for the 0.280 g/cc insert. In contrast, no such trend was observed in the δ or δ95% of Synchrony treatment using the Gen2 kV system. The δ and δ95%, respectively, fluctuated slightly from 1.586 to 1.687 mm and from 2.874 to 2.971 mm when different target inserts were tracked by the Gen2 kV system.
With improved image contrast in kV radiographs, the Gen2 kV imaging system can enhance the ability to track targets accurately in Radixact Lung Synchrony treatment and reduce the segmentation error. Our study showed that lung targets with density values as low as 0.280 cc/g could be tracked correctly in Synchrony treatment with the Gen2 kV imaging system.
目的是研究在ClearRT™装置中,Radixact Synchrony肺部治疗的千伏成像系统从第1代升级到第2代后,分割误差的变化情况。
为18023型Xsight肺部追踪“XLT”体模创建Radixact肺部同步计划,该体模结合了密度分别为0.280、0.500、0.943和1.093 g/cc的不同肺部靶区插入物。根据每个计划,使用第1代和第2代千伏系统进行Radixact同步治疗后,通过计算日志文件中同步预测运动与已知体模运动之间的均方根(RMS)误差(δ)以及计算δ95%(95%概率阈值内的最大误差),比较两个千伏系统在每个密度插入物上的追踪性能。
第1代千伏系统的Radixact同步治疗的δ和δ95%随着靶区插入物密度的降低而恶化,对于1.093 g/cc的插入物,分别为1.673±0.064 mm和3.049±0.089 mm,对于0.280 g/cc的插入物,分别为8.355±5.873 mm和15.297±10.470 mm。相比之下,使用第2代千伏系统的同步治疗的δ或δ95%未观察到这种趋势。当第2代千伏系统追踪不同靶区插入物时,δ和δ95%分别在1.586至1.687 mm和2.874至2.971 mm之间略有波动。
随着千伏射线照片图像对比度的提高,第2代千伏成像系统可以增强在Radixact肺部同步治疗中准确追踪靶区的能力并减少分割误差。我们的研究表明,使用第2代千伏成像系统在同步治疗中可以正确追踪密度低至0.280 cc/g的肺部靶区。