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螺旋断层放疗:慕尼黑工业大学 Hi-ART 和 Radixact 临床患者治疗的比较。

Helical tomotherapy: Comparison of Hi-ART and Radixact clinical patient treatments at the Technical University of Munich.

机构信息

Technichal University of Munich (TUM), Klinikum rechts der Isar, Department of Radiation Oncology, München, Germany.

Helmholtz Zentrum München (HMGU), Institute of Radiation Medicine (IRM), Department of Radiation Sciences (DRS), Neuherberg, Germany.

出版信息

Sci Rep. 2020 Mar 18;10(1):4928. doi: 10.1038/s41598-020-61499-w.

Abstract

The helical tomotherapy (HT) Hi-ART system was installed at our department in April 2007. In July 2018 the first Radixact system in Germany has been launched for clinical use. We present differences, advantages and disadvantages and show future perspectives in patient treatment using two HT devices. We investigate patient characteristics, image quality, radiotherapy treatment specifications and analyze the time effort for treatments with the Hi-ART system from April 2010 until May 2017 and compare it to the data acquired in the first nine months of usage of the Radixact system. Comparing the Hi-ART and Radixact system, the unique option of integrated MVCT image acquisition has experienced distinct improvement in image quality. Time effort for irradiation treatment could be improved resulting in a mean beam on time for craniospinal axis treatment of 636.2 s for the Radixact system compared to 915.9 s for the Hi-ART system. The beneficial use of tomotherapy for complex target volumes is demonstrated by a head and neck tumor case and craniospinal axis treatment. With the Radixact system MVCT image quality has been improved allowing for fast and precise interfraction dose adaptation. The improved time effort for patient treatment could increase the accessibility for clinical usage.

摘要

螺旋断层放疗(HT)Hi-ART 系统于 2007 年 4 月在我科安装。2018 年 7 月,德国第一台 Radixact 系统开始临床应用。我们展示了使用两种 HT 设备在患者治疗方面的差异、优势和劣势,并展示了未来的治疗前景。我们研究了患者特征、图像质量、放射治疗规范,并分析了 2010 年 4 月至 2017 年 5 月使用 Hi-ART 系统进行治疗的时间和工作量,并将其与 Radixact 系统前九个月的数据进行比较。与 Hi-ART 系统相比,Radixact 系统独特的集成 MVCT 图像采集功能显著提高了图像质量。照射治疗的时间和工作量得到了改善,导致颅脊柱轴治疗的平均束流时间为 Radixact 系统的 636.2s,而 Hi-ART 系统的 915.9s。通过一个头颈部肿瘤病例和颅脊柱轴治疗,展示了 Tomotherapy 在复杂靶区治疗中的优势。Radixact 系统的 MVCT 图像质量得到了改善,允许快速、精确的分次剂量调整。患者治疗的时间和工作量的改善可能会增加临床应用的可及性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c05/7080845/a7a3cb437a2d/41598_2020_61499_Fig1_HTML.jpg

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