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螺旋断层放射治疗用于肺和肝肿瘤的肿瘤追踪放疗的首例报告:双病例报告

A first report of tumour-tracking radiotherapy with helical tomotherapy for lung and liver tumours: A double case report.

作者信息

Okada Wataru, Doi Hiroshi, Tanooka Masao, Sano Keisuke, Nakamura Kenji, Sakai Yusuke, Shibata Mayuri, Tanaka Masahiro

机构信息

Department of Radiotherapy, Takarazuka City Hospital, Takarazuka, Japan.

Department of Radiation Oncology, Faculty of Medicine, Kindai University, Osaka, Japan.

出版信息

SAGE Open Med Case Rep. 2021 Jun 12;9:2050313X211023688. doi: 10.1177/2050313X211023688. eCollection 2021.

Abstract

There are only a limited number of previous reports on clinical cases using tumour tracking with tomotherapy. Therefore, we present two cases of patients treated with tumour tracking with tomotherapy. First, a 74-year-old man with an inoperable lung cancer type T1bN0M0 underwent stereotactic body radiotherapy at a total dose of 48 Gy in four fractions. Second, a 68-year-old man with hepatocellular carcinoma with a portal venous tumour thrombosis and history of liver stereotactic body radiotherapy with fiducial marker implantation received radiotherapy at a total dose of 48 Gy in 20 fractions. The results of patient-specific quality assurance and tracking radiotherapy were sufficient to irradiate tumours. Tumour tracking with tomotherapy successfully delivered radiation in a total of 24 treatment fractions in both patients. Tumour tracking with tomotherapy is feasible in lung and liver cancer treatment. This study's findings suggest the clinical use of tumour tracking with tomotherapy.

摘要

此前关于使用断层放射治疗进行肿瘤追踪的临床病例报告数量有限。因此,我们呈现两例使用断层放射治疗进行肿瘤追踪的患者病例。第一例,一名74岁的男性,患有无法手术切除的T1bN0M0期肺癌,接受了立体定向体部放射治疗,总剂量为48 Gy,分4次给予。第二例,一名68岁的男性,患有肝细胞癌并伴有门静脉肿瘤血栓形成,有肝脏立体定向体部放射治疗并植入基准标记物的病史,接受了放射治疗,总剂量为48 Gy,分20次给予。针对患者的质量保证和追踪放射治疗结果足以对肿瘤进行照射。在两名患者中,断层放射治疗的肿瘤追踪均成功在总共24个治疗分次中输送了辐射。断层放射治疗的肿瘤追踪在肺癌和肝癌治疗中是可行的。本研究结果提示了断层放射治疗肿瘤追踪的临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1137/8202334/e633d8ec1150/10.1177_2050313X211023688-fig1.jpg

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