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抗人类嗜T淋巴细胞病毒III型抗体与高危人群的淋巴细胞亚群

Antibodies anti-HTLV III and lymphocyte subsets of high risk subjects.

作者信息

Ripa S, Mignini F, Anichini M, Casprini P, Prenna M

机构信息

Department Cellular Biology, University of Camerino.

出版信息

Boll Ist Sieroter Milan. 1987;66(2):101-5.

PMID:3663335
Abstract

208 assay for the research into anti-HTLV III antibodies and lymphocytes subsets were carried out on the same number of patients at risk. 11 homosexual man, 143 intravenous drug users (i.d.u.) and 3 children of drug addicts from hospitals in the Marche and Abruzzo and 51 haemophiliacs from hospital in Florence were examined. 3 determination of anti-HTLV III antibodies were taken from each subject using 3 different commercial Kits. The results concur with and confirm similar epidemiological studies that have been done. The haemophiliac group had the highest positive percentage (39.2%), then came i.d.u. (11.9%) and the homosexuals (10.0%). Furthermore, of the 38 positive totals, there were 22 with only one kit, 18 with two, and 15 with all three. The evaluation of the lymphocyte subsets did not strictly correlate with the presence of the antiretrovirus antibodies.

摘要

对相同数量的高危患者进行了208次抗人类嗜T淋巴细胞病毒III型抗体及淋巴细胞亚群检测。检测对象包括11名同性恋男性、143名静脉注射吸毒者(i.d.u.)、来自马尔凯和阿布鲁佐地区医院的3名吸毒者子女以及佛罗伦萨医院的51名血友病患者。使用3种不同的商业试剂盒对每个受试者进行3次抗人类嗜T淋巴细胞病毒III型抗体检测。结果与已开展的类似流行病学研究一致并得到证实。血友病患者组的阳性率最高(39.2%),其次是静脉注射吸毒者(11.9%)和同性恋者(10.0%)。此外,在38例阳性总数中,仅一种试剂盒检测为阳性的有22例,两种试剂盒检测为阳性的有18例,三种试剂盒检测均为阳性的有15例。淋巴细胞亚群的评估结果与抗逆转录病毒抗体的存在情况并无严格关联。

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