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Increasing inosine/decreasing ENT1: promising strategies for anti-obesity therapy.

作者信息

Yan Lei, Tang Yong

机构信息

International Collaborative Centre On Big Science Plan for Purinergic Signalling, School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

School of Health and Rehabilitation, Acupuncture and Chronobiology Key Laboratory of Sichuan Province, Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, China.

出版信息

Purinergic Signal. 2023 Jun;19(2):383-385. doi: 10.1007/s11302-023-09920-7. Epub 2023 Jan 12.

DOI:10.1007/s11302-023-09920-7
PMID:36633804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10247931/
Abstract
摘要

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Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.凋亡的棕色脂肪细胞通过细胞外肌苷酸促进能量消耗。
Nature. 2022 Sep;609(7926):361-368. doi: 10.1038/s41586-022-05041-0. Epub 2022 Jul 5.
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Towards a personalised approach for obesity treatment: one size does not fit all.
Heart. 2021 Oct;107(19):1526-1527. doi: 10.1136/heartjnl-2021-319726. Epub 2021 Jul 29.
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From purines to purinergic signalling: molecular functions and human diseases.从嘌呤到嘌呤能信号转导:分子功能与人类疾病。
Signal Transduct Target Ther. 2021 Apr 28;6(1):162. doi: 10.1038/s41392-021-00553-z.
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Brown adipose tissue is associated with cardiometabolic health.棕色脂肪组织与心脏代谢健康有关。
Nat Med. 2021 Jan;27(1):58-65. doi: 10.1038/s41591-020-1126-7. Epub 2021 Jan 4.