氯霉素和氰化物对细胞内噬菌体T1紫外线抗性增加的影响。
Effect of chloramphenicol and cyanide on the increase in UV resistance of intracellular bacteriophage T1.
作者信息
Mosin A F
出版信息
Microbios. 1978;20(80):125-31.
The effects of chloramphenicol and cyanide on the increase in UV resistance of intracellular phage T1 infecting cells of E. coli B or E. coli Bs-1 were investigated. The inhibitiors were added to the cells 3 min prior to infection and to the complexes of phage-bacteria 3.5 and 6.5 min after adsorption of phage by the cells. The data obtained are not in agreement with the suggestion that increase in UV resistance of intracellular phage is mainly due to the accumulation of phage DNA inside the host cells. It is suggested that a very important role in this resistance is played by the interaction of phage DNA with the cell membranes.
研究了氯霉素和氰化物对感染大肠杆菌B或大肠杆菌Bs - 1细胞的胞内噬菌体T1紫外线抗性增加的影响。在感染前3分钟将抑制剂加入细胞中，并在噬菌体吸附到细胞后3.5分钟和6.5分钟加入到噬菌体 - 细菌复合物中。所获得的数据与胞内噬菌体紫外线抗性增加主要是由于噬菌体DNA在宿主细胞内积累的观点不一致。有人提出，噬菌体DNA与细胞膜的相互作用在这种抗性中起非常重要作用。
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