恶性高热与异氟烷。病例报告。

Malignant hyperpyrexia and isoflurane. A case report.

作者信息

Thomas D W, Dev V J, Whitehead M J

机构信息

Department of Anaesthetics, Morriston Hospital, Cwmrhydyceirw, Swansea.

出版信息

Br J Anaesth. 1987 Sep;59(9):1196-8. doi: 10.1093/bja/59.9.1196.

DOI:10.1093/bja/59.9.1196

PMID:3663443

Abstract

Malignant hyperpyrexia developed, and was successfully treated, in a 50-year old man undergoing pyelolithotomy. Early diagnosis with the assistance of end-tidal carbon dioxide monitoring facilitated prompt treatment with i.v. dantrolene. A positive muscle biopsy subsequently confirmed the diagnosis. The only likely triggering agent used was isoflurane.

摘要

一名50岁接受肾盂切开取石术的男性发生了恶性高热，并得到成功治疗。在呼气末二氧化碳监测的辅助下早期诊断，促使及时静脉注射丹曲林进行治疗。随后肌肉活检呈阳性证实了诊断。唯一可能的触发药物是异氟烷。