Staropoli Patrick C, Moolani Harsh V, Elhusseiny Abdelrahman M, Flynn Harry W, Smiddy William E
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Department of Ophthalmology, Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Clin Ophthalmol. 2023 Jan 5;17:47-52. doi: 10.2147/OPTH.S394933. eCollection 2023.
Identify the long-term rate of fellow eye full-thickness macular hole (FTMH) development.
In this single site, single provider retrospective consecutive case series, idiopathic FTMH patients who underwent surgery from 2003 to 2014 who also had at least 5 years of follow-up information within our electronic medical record (EMR) which was started in 2014 were identified. Cases with secondary causes (ie, trauma), high myopia, bilateral FTMH on presentation, previous retinal surgery, retinal breaks, or intraocular inflammation were excluded. Demographics, medical and ocular history, refractive error, phakic status, best corrected visual acuity, follow-up duration, surgical technique, single operation anatomic success, and reoperations were recorded.
The rate of fellow eye FTMH was 2.6% (2/77) at 1 year, 5.2% (4/77) at 3 years, 9.1% (6/66) at 6 years, and 9.1% (7/77) as of final follow up. There were 2 cases by year 1, 2 additional cases by year 3, 2 additional cases by year 6, and 1 additional case reported thereafter. The average follow up was 11.1 ± 4.5 years. There was no significant difference in visual outcomes between primary eyes and fellow eyes. There was no significant difference in gender, age, ocular comorbidities, refractive error, phakic status, and visual acuity between the unilateral and bilateral groups.
The rate of FTMH in the fellow eye was low but significant, increased during long-term follow up, and may stabilize after 6 years.
确定对侧眼全层黄斑裂孔（FTMH）的长期发生率。
在这个单中心、由单一医生进行的回顾性连续病例系列研究中，纳入了2003年至2014年接受手术治疗的特发性FTMH患者，这些患者在我们始于2014年的电子病历（EMR）系统中至少有5年的随访信息。排除有继发原因（如外伤）、高度近视、初诊时双眼FTMH、既往视网膜手术史、视网膜裂孔或眼内炎症的病例。记录患者的人口统计学资料、医学和眼部病史、屈光不正、晶状体状态、最佳矫正视力、随访时间、手术技术、单次手术的解剖学成功率以及再次手术情况。
对侧眼FTMH的发生率在1年时为2.6%（2/77），3年时为5.2%（4/77），6年时为9.1%（6/66），截至最终随访时为9.1%（7/77）。1年时出现2例，3年时新增2例，6年时新增2例，此后又报告了1例。平均随访时间为11.1±4.5年。患眼和对侧眼的视力结果无显著差异。单眼和双眼组在性别、年龄、眼部合并症、屈光不正、晶状体状态和视力方面无显著差异。
对侧眼FTMH的发生率较低但具有统计学意义，在长期随访中有所增加，6年后可能趋于稳定。
