Chen Qingqing, Zhang Ruizhong, Dang Yanfeng
Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University, Tianjin 300072, China.
Org Biomol Chem. 2023 Feb 8;21(6):1138-1142. doi: 10.1039/d2ob02161g.
Mechanistic studies reveal that the decarboxylative allylation of amino esters dual photoredox and palladium catalysis occurs oxidation giving π-allyl-Pd(II) species and carboxylate, which is oxidized by *Ir(III)-catalyst offering benzyl radicals. The alkylated product is formed an S2 pathway. Single-electron transfer between Pd(I)-species and Ir(II)-catalysis restores both catalysts.
机理研究表明，氨基酯的脱羧烯丙基化反应通过双光氧化还原和钯催化发生，氧化生成π-烯丙基-Pd(II)物种和羧酸盐，羧酸盐被*Ir(III)催化剂氧化生成苄基自由基。烷基化产物通过S2途径形成。Pd(I)物种和Ir(II)催化之间的单电子转移使两种催化剂得以恢复。
