[Aminazine--highly effective inhibitor of tubulin polymerization].

Aminasine was found to repress tubulin polymerization into microtubules. This process is associated with the formation of anomalous structures--aggregates which contain, except tubulin, an increased amount of microtubule-associating proteins. The effect of aminasine on microtubules is specific, since it can be observed both in vitro and in vivo. Aminasine seems to be a helpful tool in studying the functions of tubulin and microtubules.