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计算机断层扫描在前列腺癌放射治疗中的应用

Computed tomography in radiotherapy of prostatic carcinoma.

作者信息

Allain Y M, Dixon B, Cellier P, Gamelin E, Geslin J, Larra F, Malkani K, Souaille C, Tuchais C

机构信息

Centre Paul-Papin, Angers, France.

出版信息

Bull Cancer. 1987;74(4):407-13.

PMID:3663963
Abstract

Hundred forty-four correlations are reported between radiological simulation and CT-scan in cases of prostate adenocarcinoma without metastases treated from 1980 to 1986 exclusively by transcutaneous radiotherapy using the box technique with 25 MV photons. Forty-eight percent of the cases were intracapsular forms. On the basis of correlation criteria defined, the prostatic boost volume was shifted in the sagittal plan in 18% of the cases. Suspect seminal vesicles were found in 60% of the cases. Our treatment plans were considered "correct" in 65% of the cases, "acceptable" in 26% of the cases and "unsatisfactory" in 29% of the cases. The corrections applied to the treatment plan do not vary according to grade but according to stage and concern mainly the posterior limit of the boost volume and to a lesser extent the superior and anterior limits. The boost volume should be determined specifically for each case. CT-scans thus seem indispensable in establishing treatment plans in prostate cancer.

摘要

报告了1980年至1986年间仅采用箱形技术、使用25兆伏光子进行经皮放疗治疗的无转移前列腺腺癌病例中,放射模拟与CT扫描之间的144种相关性。48%的病例为包膜内型。根据所定义的相关性标准,18%的病例中前列腺加量体积在矢状面发生了偏移。60%的病例中发现可疑精囊。我们的治疗计划在65%的病例中被认为“正确”,26%的病例中“可接受”,29%的病例中“不满意”。应用于治疗计划的修正并非根据分级而变化,而是根据分期,主要涉及加量体积的后界,在较小程度上涉及上界和前界。加量体积应针对每个病例具体确定。因此,CT扫描在制定前列腺癌治疗计划中似乎不可或缺。

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