Pilepich M V, Prasad S C, Perez C A
Int J Radiat Oncol Biol Phys. 1982 Feb;8(2):235-9. doi: 10.1016/0360-3016(82)90519-3.
Pretreatment computed tomography (CT) scanning of the pelvis was performed in 100 consecutive patients with carcinoma of the prostate treated with external irradiation (82 patients) or interstitial I125 (18 patients). Treatment plan modifications prompted by CT scan findings were most frequent in patients with (clinical) involvement of the seminal vesicles in whom the conventional treatment planning often resulted in an underestimate of tumor volume. Seventeen of 32 (53%) such patients required an enlargement of treatment fields to adequately encompass the target volume. Using skeletal landmarks as reference, the dimensions of the prostate, seminal vesicles and the detectable tumor and their topographic relationships were systematically tabulated. These measurements provide a basis for the definition of the target volume in patients with carcinoma of the prostate in whom CT scans might not be available.
对100例接受外照射（82例）或I125组织间插植治疗（18例）的前列腺癌患者进行了骨盆预处理计算机断层扫描（CT）。在精囊（临床）受累的患者中，CT扫描结果促使治疗计划修改的情况最为常见，在这些患者中，传统治疗计划常常导致肿瘤体积估计不足。32例此类患者中有17例（53%）需要扩大治疗野以充分覆盖靶区。以骨骼标志为参照，系统列出前列腺、精囊和可检测肿瘤的尺寸及其地形关系。这些测量结果为无法进行CT扫描的前列腺癌患者靶区的定义提供了依据。
