Augustin Mary Ann, Hartley Carol J, Maloney Gregory, Tyndall Simone
CSIRO Agriculture & Food, Werribee, VIC, Australia.
CSIRO Land & Water, ACT, Australia.
Crit Rev Food Sci Nutr. 2024 Jun;64(18):6218-6238. doi: 10.1080/10408398.2023.2166014. Epub 2023 Jan 14.
A transformation in our food production system is being enabled by the convergence of advances in genome-based technologies and traditional fermentation. Science at the intersection of synthetic biology, fermentation, downstream processing for product recovery, and food science is needed to support technology development for the production of fermentation-derived food ingredients. The business and markets for fermentation-derived ingredients, including policy and regulations are discussed. A patent landscape of fermentation for the production of alternative proteins, lipids and carbohydrates for the food industry is provided. The science relating to strain engineering, fermentation, downstream processing, and food ingredient functionality that underpins developments in precision fermentation for the production of proteins, fats and oligosaccharides is examined. The production of sustainably-produced precision fermentation-derived ingredients and their introduction into the market require a transdisciplinary approach with multistakeholder engagement. Successful innovation in fermentation-derived ingredients will help feed the world more sustainably.
基于基因组的技术进步与传统发酵技术的融合,正在推动我们的食品生产系统发生变革。合成生物学、发酵、产品回收的下游加工以及食品科学交叉领域的科学研究,对于支持发酵衍生食品成分生产的技术开发至关重要。文中讨论了发酵衍生成分的商业和市场,包括政策与法规。还提供了用于食品工业生产替代蛋白质、脂质和碳水化合物的发酵专利情况。审视了与菌株工程、发酵、下游加工以及食品成分功能相关的科学,这些科学支撑着用于生产蛋白质、脂肪和低聚糖的精准发酵技术的发展。可持续生产的精准发酵衍生成分的生产及其推向市场需要跨学科方法以及多方利益相关者的参与。发酵衍生成分的成功创新将有助于更可持续地养活世界。