Departamento de Inteligencia Artificial, ETSIINF, Universidad Politécnica de Madrid, 28040, Madrid, Spain.
Departamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid (UC3M), Leganés, 28911, Madrid, Spain.
Methods. 2023 Feb;210:36-43. doi: 10.1016/j.ymeth.2023.01.001. Epub 2023 Jan 11.
Standard molecular biology laboratories are usually made with complex, sophisticated, and expensive equipment. Unfortunately, most of these labs are not affordable for everyone. In this paper, we show how we built a portable bio lab BioBlocksLab, made of four modules: a centrifuge, a thermocycler, electrophoresis, and an incubator. We also propose a new version of a blockly programming language to describe experimental lab protocols, called BioBlocks 2.0, which is based on the Microsoft MakeCode platform from the open-source project Microsoft Programming Experience Toolkit (PXT). We run BioBlocks programs of real lab protocols to control different hardware modules with biological reagents and get positive results. We offer an easy, affordable, and open-source way for everyone to do experiments with Do-It-Yourself (DIY) portable bio-labs.
标准的分子生物学实验室通常配备复杂、精密且昂贵的设备。不幸的是，这些实验室大多数人都无法负担。在本文中，我们展示了如何构建一个便携式生物实验室 BioBlocksLab，它由四个模块组成：离心机、热循环仪、电泳仪和孵育器。我们还提出了一种新的基于 Microsoft MakeCode 平台的块编程语言来描述实验实验室协议，称为 BioBlocks 2.0，它来自开源项目 Microsoft 编程体验工具包（PXT）。我们运行使用生物试剂控制不同硬件模块的真实实验室协议的 BioBlocks 程序，并获得了积极的结果。我们提供了一种简单、经济实惠且开源的方式，让每个人都可以使用 DIY 便携式生物实验室进行实验。
