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Line-field confocal optical coherence tomography for three-dimensional skin imaging.

作者信息

Ogien Jonas, Daures Anthony, Cazalas Maxime, Perrot Jean-Luc, Dubois Arnaud

机构信息

DAMAE Medical, Paris, 75013, France.

CHU St-Etienne, Service Dermatologie, Saint-Etienne, 42055, France.

出版信息

Front Optoelectron. 2020 Dec;13(4):381-392. doi: 10.1007/s12200-020-1096-x. Epub 2020 Dec 23.


DOI:10.1007/s12200-020-1096-x
PMID:36641566
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9743950/
Abstract

This paper reports on the latest advances in line-field confocal optical coherence tomography (LC-OCT), a recently invented imaging technology that now allows the generation of either horizontal (x × y) section images at an adjustable depth or vertical (x × z) section images at an adjustable lateral position, as well as three-dimensional images. For both two-dimensional imaging modes, images are acquired in real-time, with real-time control of the depth and lateral positions. Three-dimensional (x × y × z) images are acquired from a stack of horizontal section images. The device is in the form of a portable probe. The handle of the probe has a button and a scroll wheel allowing the user to control the imaging modes. Using a supercontinuum laser as a broadband light source and a high numerical microscope objective, an isotropic spatial resolution of ∼1 µm is achieved. The field of view of the three-dimensional images is 1.2 mm × 0.5 mm × 0.5 mm (x × y × z). Images of skin tissues are presented to demonstrate the potential of the technology in dermatology.

摘要

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本文引用的文献

[1]
Line-field confocal optical coherence tomography-Practical applications in dermatology and comparison with established imaging methods.

Skin Res Technol. 2021-5

[2]
Tridimensional skin imaging in aquagenic keratoderma: virtual histology by line-field confocal optical coherence tomography.

Int J Dermatol. 2021-2

[3]
In vivo characterization of healthy human skin with a novel, non-invasive imaging technique: line-field confocal optical coherence tomography.

J Eur Acad Dermatol Venereol. 2020-12

[4]
New findings in non-invasive imaging of aquagenic keratoderma: Line-field optical coherence tomography, dermoscopy and reflectance confocal microscopy.

Skin Res Technol. 2020-11

[5]
Kaposi sarcoma of the glans: New findings by line field confocal optical coherence tomography examination.

Skin Res Technol. 2021-3

[6]
In vivo imaging of Sarcoptes scabiei infestation using line-field confocal optical coherence tomography.

J Eur Acad Dermatol Venereol. 2020-12

[7]
Mirau-based line-field confocal optical coherence tomography.

Opt Express. 2020-3-16

[8]
Dual-mode line-field confocal optical coherence tomography for ultrahigh-resolution vertical and horizontal section imaging of human skin .

Biomed Opt Express. 2020-2-10

[9]
Examination of circumscribed palmar hypokeratosis with line-field confocal optical coherence tomography: Dermoscopic, ultrasonographic and histopathologic correlates.

Indian J Dermatol Venereol Leprol. 2020

[10]
The actinic dysplasia syndrome - diagnostic approaches defining a new concept in field carcinogenesis with multiple cSCC.

J Eur Acad Dermatol Venereol. 2019-12

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