Sharma M Neha, Rajasekar Arvina
Departments of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
J Adv Pharm Technol Res. 2022 Nov;13(Suppl 1):S293-S296. doi: 10.4103/japtr.japtr_176_22. Epub 2022 Nov 30.
Periodontal disease, a persistent inflammatory condition affecting the tissues around the teeth, is brought on by an imbalance between dental biofilm and the host's reaction, with the potential for tooth loss. Periodontal disease has been linked to an excess of free radicals induced by oxidative stress or antioxidant deficiency. There is a notable oxidative process early in the course of periodontal disease, especially in periodontitis. The objective of the study is to assess if berry supplements can be used as a supplement to nonsurgical periodontal therapy. Forty individuals with chronic periodontitis in total were divided into two groups for this study. Group A received scaling and root planing (SRP), whereas Group B received SRP plus berry supplements. At baseline and on the 28 day, both groups had their probing pocket depth (PPD) and clinical attachment level (CAL) assessed. After then, the data from both time periods were compared. The SPSS software was used to examine the data (Version 23.0). Using an unpaired -test, the mean PPD and CAL values were compared between the groups. The mean PPD in Group A decreased on day 28 from 4.18 ± 0.12 to 3.06 ± 0.02 while in Group B reduced from 4.21 ± 0.13 to 2.05 ± 0.08. The CAL in Group A improved from 5.05 ± 0.09 to 3.04 ± 0.11 and in Group B from 4.52 ± 0.17 to 2.02 ± 0.08. There was evidence of a statistically significant difference between two groups in terms of mean pocket depth and clinical attachment degree ( < 0.05). Therefore, berries may be an effective treatment for chronic periodontitis when used in conjunction with SRP.
牙周病是一种影响牙齿周围组织的持续性炎症，由牙菌斑与宿主反应之间的失衡引起，存在牙齿脱落的风险。牙周病与氧化应激或抗氧化剂缺乏诱导的自由基过量有关。在牙周病病程早期，尤其是在牙周炎中，存在明显的氧化过程。本研究的目的是评估浆果补充剂是否可作为非手术牙周治疗的补充。本研究共将40名慢性牙周炎患者分为两组。A组接受龈上洁治和根面平整（SRP），而B组接受SRP加浆果补充剂。在基线和第28天时，对两组患者的探诊袋深度（PPD）和临床附着水平（CAL）进行评估。然后，比较两个时间段的数据。使用SPSS软件（版本23.0）检查数据。使用不成对t检验比较两组之间的平均PPD和CAL值。A组第28天的平均PPD从4.18±0.12降至3.06±0.02，而B组从4.21±0.13降至2.05±0.08。A组的CAL从5.05±0.09改善至3.04±0.11，B组从4.52±0.17改善至2.02±0.08。两组在平均袋深度和临床附着程度方面存在统计学显著差异（P<0.05）。因此，浆果与SRP联合使用时可能是治疗慢性牙周炎的有效方法。
