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血清乳酸作为多种病症急诊科患者死亡率预后标志物的作用:一项系统评价。

Role of serum lactate as prognostic marker of mortality among emergency department patients with multiple conditions: A systematic review.

作者信息

Alshiakh Safinaz M

机构信息

Department of Emergency Medicine, Faculty of Medicine, King AbdulAziz University, Jeddah, Saudi Arabia.

Department of Emergency Medicine, King AbdulAziz University Hospital, Jeddah, Saudi Arabia.

出版信息

SAGE Open Med. 2023 Jan 10;11:20503121221136401. doi: 10.1177/20503121221136401. eCollection 2023.

DOI:10.1177/20503121221136401
PMID:36643203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9834787/
Abstract

OBJECTIVE

In the Emergency Department, the physician's purpose is to rapidly and accurately diagnose the severity of a patient's condition so that proper treatment can be administered. Therefore, this study pays close attention to the association and prognostic value of blood lactate on different disease outcomes by systematically reviewing recently published studies.

METHODS

The search strategy was developed based on searches in the year 2022 for potential publications including original articles, case reports, and reviews using the following web databases google scholar, PubMed, and Science Direct. A total of 25 studies were identified and reviewed extensively to evaluate the link between mortality and serum lactate levels.

RESULTS

This literature review presents the strong association of elevated serum lactate levels with the in-hospital mortality rate among emergency department patients.

CONCLUSION

These findings suggest that even a moderately raised lactate level in serum can predict the severe outcome in emergency department patients suffering from different conditions. Therefore, early (at the time of administration of hospital) and periodic serum lactate value determination through different techniques and scores is of need and should become part of routine analyses in emergency department to predict and choose therapies that could benefit critically ill patients.

摘要

目的

在急诊科,医生的目的是快速准确地诊断患者病情的严重程度,以便进行适当的治疗。因此,本研究通过系统回顾近期发表的研究,密切关注血乳酸与不同疾病结局的关联及预后价值。

方法

检索策略基于2022年对潜在出版物的检索制定,包括原创文章、病例报告和综述,使用以下网络数据库:谷歌学术、PubMed和科学Direct。共识别并广泛审查了25项研究,以评估死亡率与血清乳酸水平之间的联系。

结果

本综述表明血清乳酸水平升高与急诊科患者的院内死亡率密切相关。

结论

这些发现表明,即使血清乳酸水平适度升高,也可预测急诊科不同病情患者的严重结局。因此,需要通过不同技术和评分在早期(入院时)及定期测定血清乳酸值,这应成为急诊科常规分析的一部分,以预测并选择可能使重症患者受益的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d85/9834787/87ba1d5bf61a/10.1177_20503121221136401-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d85/9834787/87ba1d5bf61a/10.1177_20503121221136401-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d85/9834787/87ba1d5bf61a/10.1177_20503121221136401-fig1.jpg

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