儿童焦虑与每日细颗粒物：一项纵向研究。
Pediatric anxiety and daily fine particulate matter: A longitudinal study.
作者信息
Vancil Andrew, Strawn Jeffrey R, Rasnick Erika, Levine Amir, Schroeder Heidi K, Specht Ashley M, Turner Ashley L, Ryan Patrick H, Brokamp Cole
机构信息
Cincinnati Children's Hospital Medical Center, Division of Biostatistics and Epidemiology, USA.
University of Cincinnati, Anxiety Disorders Research Program, Department of Psychiatry & Behavioral Neuroscience, USA.
出版信息
Psychiatry Res Commun. 2022 Dec;2(4). doi: 10.1016/j.psycom.2022.100077. Epub 2022 Oct 9.
Daily variations in ambient fine particulate matter (PM) could contribute to the morbidity of anxiety disorders in children and adolescents, but has not yet been studied longitudinally at a daily level. We tested this association using repeated weekly measures of anxiety symptom severity in a group of 23 adolescents with generalized anxiety disorder. After estimating ambient PM concentrations using a validated model, we found that increased concentrations were significantly associated with increased anxiety symptom severity and frequency two, three, and four days later. PM may be a novel, modifiable exposure that could inform population level interventions to decrease psychiatric morbidity.
环境细颗粒物（PM）的每日变化可能导致儿童和青少年焦虑症的发病，但尚未在每日水平上进行纵向研究。我们在一组23名患有广泛性焦虑症的青少年中，通过每周重复测量焦虑症状严重程度来测试这种关联。在使用经过验证的模型估算环境PM浓度后，我们发现浓度升高与两天、三天和四天后焦虑症状严重程度和频率的增加显著相关。PM可能是一种新的、可改变的暴露因素，可为降低精神疾病发病率的人群水平干预措施提供依据。
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