Gezer Emre, Piro Bejda, Cantürk Zeynep, Çetinarslan Berrin, Sözen Mehmet, Selek Alev, Polat Işik Aslıhan, Seal Leighton John
Department of Endocrinology and Metabolism and Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Department of Psychiatry, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey.
Transgend Health. 2022 Nov 29;7(6):514-520. doi: 10.1089/trgh.2021.0061. eCollection 2022 Nov.
The prevalence of polycystic ovary syndrome (PCOS) among trans men has been reported as higher than among the cisgender population, which varies between 14.4% and 58%. In this cross-sectional study, we aimed to evaluate the association of oligo-anovulation and/or features of hyperandrogenism with the scores on the Utrecht Gender Dysphoria Scale (UGDS), the Body Image Scale (BIS), and the Short Form-36 Health Survey (SF-36) in treatment-naive trans men with PCOS seeking help for gender transition. The study sample consisted of trans men who were diagnosed with gender dysphoria (GD) between December 2019 and November 2020. To assess body dissatisfaction and psychological functioning, the UGDS, BIS, and SF-36 were administered to all transgender individuals as part of the routine assessment procedure. A total of 49 treatment-naive trans men were included in our study; 38.8% (=19) of the participants were diagnosed with PCOS using the Rotterdam 2003 criteria. The scores of UGDS and BIS were significantly lower in the PCOS group compared with the non-PCOS group (<0.001 and =0.003, respectively). Among the eight parameters within SF-36, general health, emotional role, and vitality scores were significantly higher in the PCOS group (=0.031, =0.015, and =0.006, respectively). Our study is the first study that demonstrates significantly lower GD, higher body image satisfaction and quality of life in trans men with PCOS compared with those without PCOS. Our findings are promising for larger prospective cohort studies to develop a consensus on the management of PCOS in trans men.
据报道，多囊卵巢综合征（PCOS）在跨性别男性中的患病率高于顺性别群体，后者的患病率在14.4%至58%之间。在这项横断面研究中，我们旨在评估少排卵和/或高雄激素血症特征与乌得勒支性别焦虑量表（UGDS）、身体意象量表（BIS）以及简明健康状况调查量表（SF-36）得分之间的关联，研究对象为未经治疗、因性别转换寻求帮助且患有PCOS的跨性别男性。研究样本包括在2019年12月至2020年11月期间被诊断为性别焦虑症（GD）的跨性别男性。为评估身体不满和心理功能，作为常规评估程序的一部分，对所有跨性别个体进行了UGDS、BIS和SF-36评估。我们的研究共纳入了49名未经治疗的跨性别男性；根据2003年鹿特丹标准，38.8%（即19名）参与者被诊断患有PCOS。与非PCOS组相比，PCOS组的UGDS和BIS得分显著更低（分别为<0.001和=0.003）。在SF-36的八个参数中，PCOS组的总体健康、情感角色和活力得分显著更高（分别为=0.031、=0.015和=0.006）。我们的研究是第一项表明与未患PCOS的跨性别男性相比，患有PCOS的跨性别男性的GD显著更低、身体意象满意度和生活质量更高的研究。我们的研究结果为开展更大规模的前瞻性队列研究以就跨性别男性PCOS的管理达成共识带来了希望。
