Kupryjaniuk Anna, Sobstyl Michał
Institute of Psychiatry and Neurology, Neurosurgery Department in Warsaw.
Pol Merkur Lekarski. 2022 Dec 22;50(300):398-400.
In recent years, more and more attention has been paid to the deterioration of cognitive functioning after the use of chemotherapy. The article presents the problems of cognitive disorders caused by chemotherapy in cancer patients. These deficits in scientific terminology are called chemobrain. Patients in particular indicate disorders of: longterm verbal memory and executive functions (planning, verbal fluency and working memory). This is confirmed by the results of neuroimaging studies. It has been observed that higher doses of cytostatics may contribute to the development of cognitive deficits. This article is a general introduction to the problems of chemobrain - the definition of the phenomenon and a discussion of neuroanatomical issues related to the influence of chemotherapy on the central nervous system. Moreover, the article tries to draw attention to the application of neuropsychological rehabilitation after chemotherapy.
近年来，化疗后认知功能恶化越来越受到关注。本文阐述了癌症患者化疗引起的认知障碍问题。这些科学术语中的缺陷被称为化疗脑。患者尤其表现出以下方面的障碍：长期言语记忆和执行功能（计划、言语流畅性和工作记忆）。神经影像学研究结果证实了这一点。据观察，更高剂量的细胞毒性药物可能导致认知缺陷的发展。本文是对化疗脑问题的总体介绍——现象的定义以及与化疗对中枢神经系统影响相关的神经解剖学问题的讨论。此外，本文试图提请注意化疗后神经心理康复的应用。
