Moffitt Cancer Center, 12902 USF Magnolia Dr., Tampa, FL 33612, United States; University of South Florida, 4202 E Fowler Ave, Tampa, FL 33620, United States.
Moffitt Cancer Center, 12902 USF Magnolia Dr., Tampa, FL 33612, United States; University of South Florida, 4202 E Fowler Ave, Tampa, FL 33620, United States.
Drug Alcohol Depend. 2023 Mar 1;244:109768. doi: 10.1016/j.drugalcdep.2023.109768. Epub 2023 Jan 11.
The combined use of cigarettes and alcohol is associated with a synergistic increase in the risk of morbidity and mortality. Continued alcohol use during a smoking quit attempt is a considerable risk factor for smoking relapse. As such, there is a need for interventions that address both behaviors concurrently. Mindfulness-based interventions hold much promise for simultaneously addressing tobacco and alcohol use.
This pilot study evaluated the feasibility and acceptability of a mindfulness-based intervention using a two-arm randomized controlled trial of Mindfulness-Based Relapse Prevention for Smoking and Alcohol (MBRP-SA) vs Cognitive Behavioral Therapy (CBT). Interventions were delivered via telehealth in a group setting; all participants received a 6-week supply of the nicotine patch. Participants (N = 69) were adults who smoked cigarettes who reported binge drinking and were motivated to both quit smoking and change their alcohol use. Primary outcomes were feasibility and acceptability of MBRP-SA compared to CBT. Changes in tobacco and alcohol use are also presented.
Participants in MBRP-SA and CBT indicated that the treatments were highly acceptable, meeting a priori benchmarks. Feasibility was mixed with some outcomes meeting benchmarks (e.g., recruitment) and others falling below (e.g., retention). Participants in both conditions demonstrated significant reductions in tobacco and alcohol use at the end of treatment.
In sum, MBRP-SA had comparable outcomes to CBT on all metrics measured. Future research should evaluate the efficacy of MBRP-SA on smoking abstinence and drinking reductions in a large-scale, fully powered trial. This study was registered on clinicaltrials.gov (NCT03734666).
吸烟和饮酒的联合使用会导致发病率和死亡率的协同增加。在戒烟尝试期间继续饮酒是导致吸烟复发的一个重要危险因素。因此，需要同时解决这两种行为的干预措施。基于正念的干预措施为同时解决烟草和酒精使用问题提供了很大的希望。
本研究采用正念防复吸治疗吸烟和酒精（MBRP-SA）与认知行为疗法（CBT）的两臂随机对照试验，评估了基于正念的干预措施的可行性和可接受性。干预措施以小组形式通过远程医疗进行；所有参与者都收到了 6 周剂量的尼古丁贴片。参与者（N=69）为吸烟且有 binge drinking 习惯的成年人，有同时戒烟和改变饮酒习惯的动机。主要结果是 MBRP-SA 与 CBT 相比的可行性和可接受性。还介绍了烟草和酒精使用的变化。
MBRP-SA 和 CBT 组的参与者表示，治疗方法非常可接受，符合预先设定的标准。可行性好坏参半，有些结果符合标准（例如，招募），而其他结果则低于标准（例如，保留）。两种情况下的参与者在治疗结束时都显示出烟草和酒精使用的显著减少。
总的来说，MBRP-SA 在所有测量指标上的结果与 CBT 相当。未来的研究应该在一项大规模、全面的试验中评估 MBRP-SA 对戒烟和减少饮酒的疗效。这项研究在 clinicaltrials.gov 上注册（NCT03734666）。
