Neurodiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Neurodiagnostic and Neurointerventional Division, Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
J Neuroradiol. 2023 May;50(3):352-360. doi: 10.1016/j.neurad.2023.01.004. Epub 2023 Jan 14.
Following the advent of mechanical thrombectomy, occlusive clots in ischemic stroke have been amply characterized using conventional histopathology. Many studies have investigated the compositional variability of thrombi and the consequences of thrombus composition on treatment response. More recent evidence has emerged about the spatial heterogeneity of the clot or the preferential distribution of its components and compact nature. Here we review this emerging body of evidence, discuss its potential clinical implications, and propose the development of adequate characterization techniques.
随着机械取栓术的出现，缺血性脑卒中的闭塞性血栓已得到充分的常规组织病理学特征描述。许多研究调查了血栓的组成变异性及其对治疗反应的影响。最近出现了更多关于血栓的空间异质性或其成分的优先分布和致密特性的证据。本文综述了这一新兴的证据，讨论了其潜在的临床意义，并提出了开发充分特征描述技术的建议。
