不同病程形式的马角膜炎临床症状的特征。
Features of the clinical picture of keratitis in horses with different forms of the course of the disease.
机构信息
Department of Biology and General Genetics, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
Department of Regulatory Relations of Circulation of Medicines and Medical Devices, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.
出版信息
Open Vet J. 2022 Nov-Dec;12(6):830-838. doi: 10.5455/OVJ.2022.v12.i6.7. Epub 2022 Nov 13.
BACKGROUND
Keratitis is a common cause of eye diseases in horses, often resulting in complete loss of vision.
AIM
The purpose of this article is to study the features of the clinical picture of primary and secondary keratitis in horses, depending on the form of the course of the disease.
METHODS
The study was conducted in 2019 at 22 private horse breeding farms. The study involved 80 horses with keratitis, which were divided into two equal groups depending on the diagnosis of primary or secondary keratitis.
RESULTS
The effectiveness of the therapies was compared 1, 3, and 6 months after the start of treatment. Following a 1-month therapy, only a minority of horses with primary keratitis had their eye functions fully restored, the number of horses with macula was two times higher ( ≤ 0.05), the number of horses with nebula was seven times higher ( ≤ 0.001), and leukomas were reported in most of the cases ( ≤ 0.0001).
CONCLUSION
The effectiveness of the therapy for keratitis is directly related to the peculiarities of treatment and adherence to the regimen.
背景
角膜炎是马科动物常见的眼病病因，常导致视力完全丧失。
目的
本文旨在研究原发性和继发性角膜炎在疾病过程中的表现特征。
方法
本研究于 2019 年在 22 家私人马场进行，共纳入 80 例角膜炎马，根据原发性或继发性角膜炎的诊断分为两组。
结果
治疗开始后 1、3 和 6 个月时比较治疗效果。经过 1 个月的治疗，只有少数原发性角膜炎的马的眼部功能完全恢复，而有黄斑的马的数量增加了两倍（≤0.05），有云翳的马的数量增加了七倍（≤0.001），且大多数马出现了白斑（≤0.0001）。
结论
角膜炎的治疗效果与治疗的特点和方案的坚持直接相关。
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