Osborne J E, Telford D, Barr G, Roberts C
Department of Otolaryngology, Ninewells Hospital, Dundee.
Clin Otolaryngol Allied Sci. 1987 Aug;12(4):261-4. doi: 10.1111/j.1365-2273.1987.tb00199.x.
In a prospective study, 69 children admitted for adenoidectomy were divided into 4 subgroups according to their symptomatology. These were: nasal obstruction alone; glue ear; recurrent ear aches and probable otitis media; and recurrent sore throats and probable tonsillitis. The adenoids removed were bacteriologically analysed to assess both the spectrum of organisms present and the colony counts per gram of adenoid tissue (10(5) organisms per gram was regarded as representing infection). There was no significant difference between the subgroups with regard to either the presence of infection or the spectrum of organisms grown. We conclude that while infection in the adenoid bed must be involved in the pathogenesis of bacterial otitis media, the concentration of organisms present in the adenoids is unimportant and other factors must be responsible for the migration of organisms up the Eustachian tube.
在一项前瞻性研究中,69名因腺样体切除术而入院的儿童根据其症状被分为4个亚组。这些亚组分别为:仅鼻塞;胶耳;复发性耳痛及可能的中耳炎;复发性喉咙痛及可能的扁桃体炎。对切除的腺样体进行细菌学分析,以评估存在的微生物种类以及每克腺样体组织中的菌落数(每克10⁵个微生物被视为代表感染)。各亚组在感染的存在或培养出的微生物种类方面均无显著差异。我们得出结论,虽然腺样体床的感染必定参与细菌性中耳炎的发病机制,但腺样体中存在的微生物浓度并不重要,其他因素必定是导致微生物沿咽鼓管向上迁移的原因。