Maw A R, Speller D C
Clin Otolaryngol Allied Sci. 1985 Oct;10(5):265-9. doi: 10.1111/j.1365-2273.1985.tb00253.x.
In a prospective investigation of the treatment of glue ear in children, the possible role of persistent infection in the tonsils and adenoids was assessed by comparing bacterial cultures of swabs and resected tissue from the tonsils and adenoids of patients with cultures of swabs from similar sites in control subjects without ENT abnormality. For almost all potential pathogens, including Streptococcus pneumoniae and Haemophilus influenzae, no statistically significant differences were demonstrated between patients and controls. The same was true of Streptococcus pyogenes in tonsil specimens, while in adenoid specimens rather more isolates were obtained in patients than controls. This difference was just statistically significant at the 5% level, but only when all isolations, including very scanty growths, were compared. On present evidence, persistent infection should not be invoked to explain the success of adenoidectomy in otitis media with effusion or to justify adenotonsillectomy.
在一项针对儿童胶耳治疗的前瞻性研究中，通过比较患有耳鼻喉异常的患者扁桃体和腺样体拭子及切除组织的细菌培养结果与无耳鼻喉异常的对照受试者相同部位拭子的培养结果，评估了扁桃体和腺样体持续感染的可能作用。对于几乎所有潜在病原体，包括肺炎链球菌和流感嗜血杆菌，患者与对照之间均未显示出统计学上的显著差异。扁桃体标本中的化脓性链球菌情况相同，而腺样体标本中患者分离出的菌株比对照更多。这种差异仅在5%的水平上具有统计学意义，但只有在比较所有分离结果（包括生长非常稀少的情况）时才如此。根据目前的证据，不应将持续感染作为解释腺样体切除术治疗渗出性中耳炎成功的原因，也不应作为腺样体扁桃体切除术的理由。
