病毒在强直性脊柱炎或银屑病关节炎中是否起病因作用？
Do viruses play an etiologic role in ankylosing spondylitis or psoriatic arthritis?
作者信息
Luxembourg A, Cailla H, Roux H, Roudier J
机构信息
Centre d'Immunologie INSERM-CNRS de Marseille-Luminy, France.
出版信息
Clin Immunol Immunopathol. 1987 Nov;45(2):292-5. doi: 10.1016/0090-1229(87)90044-4.
High venous blood levels of 2-5A, an adenylic acid polymer synthesized in the presence of double-stranded RNA and considered as a viral replication indicator, have been found in blood samples from ankylosing spondylitis and psoriatic arthritis patients, but not from patients with seropositive rheumatoid arthritis or acute chondrocalcinosis. These findings suggest the possibility that ankylosing spondylitis and psoriatic arthritis might be virus-induced diseases.
在强直性脊柱炎和银屑病关节炎患者的血液样本中发现，2-5A（一种在双链RNA存在下合成的腺苷酸聚合物，被视为病毒复制指标）的静脉血水平较高，但血清阳性类风湿性关节炎或急性软骨钙质沉着症患者的血液样本中未发现该情况。这些发现提示强直性脊柱炎和银屑病关节炎可能是病毒诱导性疾病的可能性。
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