高剂量酮康唑治疗脑曲霉肿
High dose ketoconazole in the treatment of cerebral aspergilloma.
作者信息
Kwong Y L, Yu Y L, Chan F L, Lam K S, Woo E, Huang C Y
机构信息
University Department of Medicine, Queen Mary Hospital, Hong Kong.
出版信息
Clin Neurol Neurosurg. 1987;89(3):193-6. doi: 10.1016/s0303-8467(87)80054-9.
PMID:3665293
Abstract
A 32-year-old Chinese woman with bilateral occipital aspergilloma was treated successfully with high dose ketoconazole (1200 mg/day) for six months in conjunction with amphotericin B and 5-fluorocytosine. No unacceptable side effects occurred. The use of high dose ketoconazole could be considered in CNS aspergillosis unresponsive to conventional anti-fungal therapy.
摘要
一名32岁的中国女性患有双侧枕叶曲霉菌瘤，接受了高剂量酮康唑（1200毫克/天）治疗六个月，并联合使用两性霉素B和5-氟胞嘧啶，治疗成功。未出现不可接受的副作用。对于对传统抗真菌治疗无反应的中枢神经系统曲霉菌病，可考虑使用高剂量酮康唑。
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